Browsing by Author "Ferreira, Rafaela Salgado"
Now showing items 3-22 of 22
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Conformational restriction of aryl thiosemicarbazones produces potent and selective anti-Trypanosoma cruzi compounds which induce apoptotic parasite death
Moreira, Diogo Rodrigo Magalhaes et al. | Date Issued: 2014 -
Desing and synthesis of potent anti-Trypanosoma cruzi agents new thiazoles derivatives which induce apoptotic parasite death
Silva, Elany Barbosa da et al. | Date Issued: 2017 -
Epoxi-α-lapachona : uma nova perspectiva para quimioterapia das leishmanioses
Silva, Franklin Souza da | Date Issued: 2014O foco deste projeto é analisar os efeitos do epoxi-α-lapachona sobre Leishmania (Viannia) braziliensis e Leishmania (Leishmania) amazonensis. Inicialmente é proposto que promastigotas e amastigotas de ambas as espécies ... -
Molecular targets for Chagas disease: validation, challenges and lead compounds for widely exploited targets
Souza, Mariana Laureano de et al. | Date Issued: 2023 -
New 1,3-thiazole derivatives and their biological and ultrastructural effects on Trypanosoma cruzi
Gomes, Paulo André Teixeira de Moraes et al. | Date Issued: 2016 -
Optimization of anti-Trypanosoma cruzi oxadiazoles leads to identification of compounds with efficacy in infected mice.
Santos Filho, José Maurício dos et al. | Date Issued: 2012 -
Planejamento racional de fármacos aplicado à busca e otimização de inibidores do HIV-1 e doença de Chagas
Santos, Lucianna Helene Silva dos | Date Issued: 2016O sucesso no planejamento de fármacos de novas moléculas bioativas está relacionado com o entendimento do alvo molecular e seu valor para com a doença que deseja ser combatida. Entender as interações importantes serve como ... -
Reenacting the Birth of a Function: Functional Divergence of HIUases and Transthyretins as Inferred by Evolutionary and Biophysical Studies
Oliveira, Lucas Carrijo de et al. | Date Issued: 2021 -
Síntese, avaliação biológica e modelagem molecular de arilfuranos como inibidores da enzima tripanotiona redutase
Oliveira, Renata Barbosa de et al. | Date Issued: 2008 -
Structural design, synthesis and pharmacological evaluation of 4-thiazolidinones against Trypanosoma cruzi
Oliveira Filho, Gevanio Bezerra de et al. | Date Issued: 2015 -
Structural design, synthesis and structure-activity relationships of thiazolidinones with enhanced anti-Trypanosoma cruzi activity
Moreira, Diogo Rodrigo Magalhães et al. | Date Issued: 2014 -
Structural investigation of anti-Trypanosoma cruzi 2-iminothiazolidin-4-ones allows the identification of agents with efficacy in infected mice.
Moreira, Diogo Rodrigo Magalhães et al. | Date Issued: 2012 -
Studies toward the structural optimization of novel thiazolylhydrazone-based potent antitrypanosomal agents
Hernandes, Marcelo Zaldini et al. | Date Issued: 2010 -
Synthesis and biological evaluation of potential inhibitors of the cysteine proteases cruzain and rhodesain designed by molecular simplification
Braga, Saulo Fehelberg Pinto et al. | Date Issued: 2017 -
Synthesis and evaluation of the antiparasitic activity of bis-(arylmethylidene) cycloalkanones
Braga, Saulo F. P. et al. | Date Issued: 2014 -
Synthesis and structure-activity relationship study of a new series of antiparasitic aryloxyl thiosemicarbazones inhibiting Trypanosoma cruzi cruzain
Espíndola, José Wanderlan Pontes et al. | Date Issued: 2015 -
Synthesis and structure-activity relationship study of a new series of antiparasitic aryloxyl thiosemicarbazones inhibiting Trypanosoma cruzi cruzain.
Espíndola, José Wanderlan Pontes et al. | Date Issued: 2015 -
Synthesis of a sugar-based thiosemicarbazone series and structure-activity relationship versus the parasite cysteine proteases: rhodesain; cruzain and Schistosoma mansoni cathepsin B1
Fonseca, Nayara Cristina et al. | Date Issued: 2015 -
Synthesis of indole-based ferulic acid derivatives and in vitro evaluation of antiviral activity against SARS-CoV-2.
Verzola, Marina Marina Mol Sena Andrade et al. | Date Issued: 2023 -
Synthesis, Design, and Structure-Activity Relationship of a Benzenesulfonylpiperazine Series against Trypanosoma cruzi
Martinho, Ana Clara Cassiano et al. | Date Issued: 2022