Author | Souza, Diego Pereira de | |
Author | Gonçalves, José Francisco de Carvalho | |
Author | Carvalho, Josiane Celerino de | |
Author | Silva, Karyne Kathlen Guedes da | |
Author | Fernandes, Andreia Varmes | |
Author | Nascimento, Gleisson de Oliveira | |
Author | Ramos, Marcio Viana | |
Author | Koolen, Hector Henrique Ferreira | |
Author | Bezerra, Daniel Pereira | |
Author | Santos, Alberdan Silva | |
Access date | 2022-10-14T15:29:15Z | |
Available date | 2022-10-14T15:29:15Z | |
Document date | 2022 | |
Citation | SOUZA, Diego Pereira de et al. Untargeted metabolomics used to describe the chemical composition and antimicrobial effects of the essential oil from the leaves of Guatteria citriodora Ducke. Industrial Crops & Products, v. 186, p. 1-11, 2022. | en_US |
ISSN | 1872-633X | en_US |
URI | https://www.arca.fiocruz.br/handle/icict/55141 | |
Sponsorship | Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES).
Fundação de Amparo à Pesquisa do Estado do Amazonas (FAPEAM).
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP).
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq). | en_US |
Language | eng | en_US |
Publisher | Elsevier | en_US |
Rights | open access | en_US |
MeSH | Biological Products | en_US |
MeSH | Oils, Volatile | en_US |
Subject in Portuguese | Citronellal | en_US |
Subject in Portuguese | Citronellol | en_US |
Subject in Portuguese | Concentração inibitória | en_US |
Subject in Portuguese | Produtos naturais | en_US |
Subject in Portuguese | Integridade da membrana | en_US |
Subject in Portuguese | Óleos voláteis | en_US |
Title | Untargeted metabolomics used to describe the chemical composition and antimicrobial effects of the essential oil from the leaves of Guatteria citriodora ducke | en_US |
Type | Article | en_US |
DOI | 10.1016/j.indcrop.2022.115180 | |
Abstract | Plant oils are sources of metabolites that have enormous potential for industrial applications. Herein, the chemical profile and in vitro antimicrobial activity of the essential oil (EO) from the leaves of Guatteria citriodora Ducke (Annonaceae) have been investigated for the first time. The composition of the hydrodistilled EO was analyzed using gas chromatography-mass spectrometry (GC-MS), which permitted the identification of oxygenated monoterpenes as the most highly representative class, and included citronellal (40.99%) and citronellol (14.6%) as the main compounds. The antimicrobial activity of G. citriodora EO (GcEO) was evaluated against pathogenic bacteria and phytopathogenic fungi. The experimental design was completely randomized (CRD), and used doses for each microorganism. Gram-positive strains were the most sensitive with a minimum inhibitory concentration (MIC) of 5.0 μL mL−1, while Gram-negative strains were 10.0 μL mL−1. The most potent antifungal activity was against Alternaria alternata (MIC of 1.25 μL mL−1). In addition, it fully inhibited A. alternata conidia germination at the minimum inhibitory concentration. The nucleic acid and soluble protein contents were significantly released from the conidia of A. alternata after treatment with GcEO. Using SEM (scanning electron microscopy), morphological alterations were observed in the conidia, which indicates that a lesion in the cytoplasmic membrane is one of its mechanisms of action. Overall, these results indicate that GcEO is an antimicrobial agent with potential applications in the agriculture, food, and pharmaceutical industries. | en_US |
Affilliation | Universidade Federal de São Carlos. Departamento de Química, São Carlos, SP, Brasil. | en_US |
Affilliation | Instituto Nacional de Pesquisas da Amazônia. Laboratório de Fisiologia e Bioquímica Vegetal. Manaus, AM, Brasil. | en_US |
Affilliation | Instituto Nacional de Pesquisas da Amazônia. Laboratório de Fisiologia e Bioquímica Vegetal. Manaus, AM, Brasil. | en_US |
Affilliation | Instituto Nacional de Pesquisas da Amazônia. Laboratório de Fisiologia e Bioquímica Vegetal. Manaus, AM, Brasil. | en_US |
Affilliation | Instituto Nacional de Pesquisas da Amazônia. Laboratório de Fisiologia e Bioquímica Vegetal. Manaus, AM, Brasil. | en_US |
Affilliation | Universidade Federal do Acre. Centro Multidisciplinar. Cruzeiro do Sul, AC, Brasil. | en_US |
Affilliation | Universidade Federal do Ceará. Departamento de Bioquímica e Biologia Molecular. Fortaleza, CE, Brasil. | en_US |
Affilliation | Universidade do Estado do Amazonas. Grupo de Pesquisa em Metabolômica e Espectrometria de Massa. Manaus, AM, Brasil. | en_US |
Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil. | en_US |
Affilliation | Universidade Federal do Pará. Laboratório de Investigação Sistemática em Biotecnologia e Biodiversidade Molecular. Belém, Pará, Brasil. | en_US |
Subject | Citronellal | en_US |
Subject | Citronellol | en_US |
Subject | Inhibitory concentration | en_US |
Subject | Natural products | en_US |
Subject | Membrane integrity | en_US |
Subject | Volatile oils | en_US |
DeCS | Produtos Biológicos | en_US |
DeCS | Óleos Voláteis | en_US |