Author | Mota, Tiago Feitosa | |
Author | Sousa, Orlando Marcos Farias de | |
Author | Silva, Yuri de Jesus | |
Author | Borja, Lairton Souza | |
Author | Leite, Bruna Martins Macedo | |
Author | Solcà, Manuela da Silva | |
Author | Melo, Djalma Alves de | |
Author | Brodskyn, Claudia Ida | |
Author | Dias, Edelberto Santos | |
Author | Veras, Patrícia Sampaio Tavares | |
Author | Fraga, Deborah Bittencourt Mothé | |
Access date | 2019-10-02T14:06:02Z | |
Available date | 2019-10-02T14:06:02Z | |
Document date | 2019 | |
Citation | MOTA, Tiago Feitosa et al. Natural infection by Leishmania infantum in the Lutzomyia longipalpis population of an endemic coastal area to visceral leishmaniasis in Brazil is not associated with bioclimatic factors. PLOS Neglected Tropical Diseases, v. 13, n. 8, p. 1-17, 2019. | pt_BR |
ISSN | 1935-2727 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/36077 | |
Sponsorship | PPSUS - FAPESB (Programa de
Pesquisa para o Sistema Único de Saúde -
Fundação de Amparo a Pesquisa no Estado da
Bahia - http://www.fapesb.ba.gov.br - Grant
number: SUS0011/2010, SUS0036/2013 and PET0024/2013) for CIB and PSTV. This study was
financed in part by the Coordenação de
Aperfeiçoamento de Pessoal de Nível Superior -
Brasil (CAPES) - Finance Code 001. | pt_BR |
Language | eng | pt_BR |
Publisher | Public Library of Science | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | Leishmania infantum | pt_BR |
Subject in Portuguese | Lutzomyia | pt_BR |
Subject in Portuguese | Leishmaniose visceral | pt_BR |
Subject in Portuguese | Dipteros | pt_BR |
Subject in Portuguese | Brasil | pt_BR |
Title | Natural infection by Leishmania infantum in the Lutzomyia longipalpis population of an endemic coastal area to visceral leishmaniasis in Brazil is not associated with bioclimatic factors | pt_BR |
Type | Article | pt_BR |
DOI | 10.1371/journal.pntd.0007626 | |
Abstract | Visceral leishmaniasis (VL) is a zoonosis caused by the protozoan Leishmania infantum and in Brazil is transmitted mainly by the bite of Lutzomuyia longipalpis sand flies. Data about the presence, distribution, natural infection rate, seasonal and monthly dynamics of the vector population are important for optimizing the measures to control VL in endemic areas. This study aimed to identify sand fly fauna in an endemic area for VL to detect the prevalence of L. infantum infection in the Lu. longipalpis population and to elucidate the influence of bioclimatic factors on the monthly fluctuations of this vector. HP light traps were monthly set in the intradomicile and peridomicile of residences located in the central and beachfront areas of Camaçari, a VL endemic area. The sand fly collection was conducted in two periods: i) period 1-between December 2011 and November 2012 and ii) period 2-August 2014 and July 2015. Sand fly species were identified and detection of L. infantum infection by qPCR was performed in pools of female Lu. longipalpis. For the first time, the parasite load of positive pools was correlated with the number of Lu. longipalpis captured per month in both periods. Correlation analyses between the monthly fluctuation of the sand fly population and bioclimatic indices of the municipality in both collection periods were also performed. In both evaluated periods, more than 98% of the collected sand flies were Lu. longipalpis, confirming the predominance of this species in the region. It was captured mostly in the beachfront area in all months evaluated (99%). For the period 1, Leishmania DNA was detected in 81% of tested pools representing a minimal infection rate of 9.6%. In the period 2, 40% of the pools were positive with a minimal infection rate of 10.2%. Infected sand flies were only detected in the beachfront area in both periods. The parasite load was low and did not vary in the evaluated months despite the number of collected sand flies. No correlation was observed for climatic factors in both areas of Camaçari. These findings emphasize the high risk of Leishmania transmission in Camaçari regardless of the season and that other factors, aside from bioclimatic elements, are influencing the sand fly population monthly fluctuation. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil. | pt_BR |
Affilliation | Universidade Federal da Bahia. Escola de Escola de Medicina Veterinária e Zootecnia. Salvador, BA, Brasil. | pt_BR |
Affilliation | Centro de Controle de Zoonoses de Camaçari, Camaçari, BA, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais. Salvador, BA, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Escola de Escola de Medicina Veterinária e Zootecnia. Salvador, BA, Brasil / Instituto Nacional de Ciência e Tecnologia de Doenças Tropicais. Salvador, BA, Brasil. | pt_BR |
Subject | Leishmania infantum | pt_BR |
Subject | Lutzomyia | pt_BR |
Subject | Visceral leishmaniasis | pt_BR |
Subject | Diptera | pt_BR |
Subject | Brazil | pt_BR |