Browsing by Author "Boechat, Nubia"
Now showing items 4-23 of 24
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Avaliação do potencial terapêutico de novos agentes tripanocidas sobre o Trypanosoma cruzi
Timm, Bruno Lisboa | Date Issued: 2014O tratamento etiológico disponível para a doença de Chagas, causada pelo parasito intracelular Trypanosoma cruzi, é baseado em dois nitroderivados, benzonidazol (Bz) e nifurtimox (Nif), ambos introduzidos empiricamente na ... -
Avaliação fenotípica in vitro de novas amidinas aromáticas sobre Trypanosoma cruzi
Silva, Marianne Rocha Simões | Date Issued: 2015A doença de Chagas (DC), causada pelo protozoário Trypanosoma cruzi, é uma doença negligenciada endêmica em diferentes regiões empobrecidas da América Latina. O tratamento, baseado em dois nitroderivados, Nifurtimox e ... -
Beyond Members of the Flaviviridae Family, Sofosbuvir Also Inhibits Chikungunya Virus Replication
Ferreira, André C. et al. | Date Issued: 2019 -
Chloroquine and Sulfadoxine Derivatives Inhibit ZIKV Replication in Cervical Cells
Souza, Audrien Alves Andrade de et al. | Date Issued: 2020 -
Design, synthesis and anti-P. falciparum activity of pyrazolopyridine-sulfonamide derivatives
Silva, Thais B. et al. | Date Issued: 2016 -
Hybrids of ImatinibwithQuinoline: Synthesis,Antimyeloproliferative Activity Evaluation, and Molecular Docking
Santos, Carine et al. | Date Issued: 2022 -
Imatinib derivatives as inhibitors of K562 cells in chronic myeloid leukemia
Azevedo, Liviane D. et al. | Date Issued: 2017 -
In vitro antiviral activity of the anti-HCV drugs daclatasvir and sofosbuvir against SARS-CoV-2, the aetiological agent of COVID-19
Sacramento, Carolina Q. et al. | Date Issued: 2021 -
New 1,2,3-triazole-based analogues of benznidazole for use against Trypanosoma cruzi infection: In vitro and in vivo evaluations
Leite, Débora Inácio et al. | Date Issued: 2018 -
New Compounds Hybrids 1H-1,2,3-Triazole-Quinoline Against Plasmodium falciparum
Boechat, Nubia et al. | Date Issued: 2014 -
New hybrid trifluoromethylquinolines as antiplasmodium agents
Silva, Renata M. R. J. da et al. | Date Issued: 2019 -
New hydrazides derivatives of isoniazid against Mycobacterium tuberculosis: higher potency and lower hepatocytotoxicity
Castelo-Branco, Frederico Silva et al. | Date Issued: 2018 -
New Imatinib Derivatives with Antiproliferative Activity against A549 and K562 Cancer Cells
Oliveira, Andressa et al. | Date Issued: 2022 -
Novel 2-Nitroimidazole and Imidazooxazole Derivatives and their Activity against Trypanosoma cruzi and Mycobacterium tuberculosis
Faria, Jessica V et al. | Date Issued: 2022 -
Novel nitroimidazole derivatives evaluated for their trypanocidal, cytotoxic, and genotoxic activities
Mello, Francisco do Vale Chaves e et al. | Date Issued: 2020 -
P2X7 receptor inhibition by 2-amino-3-aryl-1,4-naphthoquinones
Martins, Daniela de Luna et al. | Date Issued: 2020 -
Synthesis and antispasmodic activity of lidocaine derivatives endowed with reduced local anesthetic action
Costa, Jorge C. S. et al. | Date Issued: 2008 -
Synthesis of polymeric nanoparticles of a high potency second generation isoniazid derivative aiming tuberculosis treatment via direct delivery to the lung
Branco, Frederico Silva Castelo et al. | Date Issued: 2023 -
Synthesis, Biological Evaluation, and Molecular Modeling Studies of New Thiadiazole Derivatives as Potent P2X7 Receptor Inhibitors
Gonzaga, Daniel T. G. et al. | Date Issued: 2019 -
The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication
Sacramento, Carolina Q. et al. | Date Issued: 2017