Use este identificador para citar ou linkar para este item: https://www.arca.fiocruz.br/handle/icict/7973

Tipo de documento
Artigo
Direito Autoral
Acesso aberto
Coleções
Compartilhar

Estatísticas
Metadata
Mostrar registro completo

HTLV TYPE 1 MOLECULAR STUDY IN BRAZILIAN VILLAGES WITH AFRICAN CHARACTERISTICS GIVING SUPPORT TO THE POST-COLUMBIAN INTRODUCTION HYPOTHESIS.
Rego, Filipe Ferreira de Almeida et al. | Data do documento: 2008
Autor(es)
Rego, Filipe Ferreira de Almeida
Alcantara, Luiz Carlos Júnior
Moura Neto, José Pereira de
Miranda, Aline Cristina Andrade Mota
Pereira, Osmario de Souza
Gonçalves, Marilda de Souza
Castro Filho, Bernardo Galvão
Afiliação
Bahia School of Medicine and Public Health. Bahia Foundation for Development of Science. Salvador, BA, Brasil / Oswaldo Cruz Foundation. Gonçalo Moniz Research Center. Advanced Public Health Laboratory. Salvador, BA, Brasil
Bahia School of Medicine and Public Health. Bahia Foundation for Development of Science. Salvador, BA, Brasil / Oswaldo Cruz Foundation. Gonçalo Moniz Research Center. Advanced Public Health Laboratory. Salvador, BA, Brasil
Oswaldo Cruz Foundation. Gonçalo Moniz Research Center. Pathology and Molecular Biology Laboratory. Salvador, BA, Brasil
swaldo Cruz Foundation. Gonçalo Moniz Research Center. Advanced Public Health Laboratory. Salvador, BA, Brasil
Oswaldo Cruz Foundation. Gonçalo Moniz Research Center. Pathology and Molecular Biology Laboratory. Salvador, BA, Brasil
Oswaldo Cruz Foundation. Gonçalo Moniz Research Center. Pathology and Molecular Biology Laboratory. Salvador, BA, Brasil
Bahia School of Medicine and Public Health. Bahia Foundation for Development of Science. Salvador, BA, Brasil / Oswaldo Cruz Foundation. Gonçalo Moniz Research Center. Advanced Public Health Laboratory. Salvador, BA, Brasil
Resumo em Inglês
We performed an HTLV epidemiological study of 986 individuals from 17 villages from the same state of Salvador, the city with the highest HTLV-1 prevalence in Brazil. The HTLV-1 prevalence was 3.85%, 1.56%, and 1.23% in three villages. Phylogenetic analysis of the LTR region demonstrated that all positive samples analyzed belonged to the Transcontinental subgroup of the HTLV-1 Cosmopolitan subtype. Three of the new HTLV- 1 sequences formed a well-supported clade within one of the Latin American clusters that contain a South African sequence. This Latin American cluster that segregated from the same ancestor as the other clade contained a Central African sequence. This ancestral relationship could support our previous report that suggests that this subgroup was first introduced into South Africa as a result of the migration of the Bantu population from Central Africa to Southern Africa over the past 3000 years, and afterward to Brazil during the slave trade between the sixteenth and nineteenth centuries.
DeCS
Infecções por HTLV-I/epidemiologia
Vírus 1 Linfotrópico T Humano/genética
Epidemiologia Molecular
Brasil/epidemiologia
Migração Internacional
Vírus 1 Linfotrópico T Humano/classificação
Humanos
Dados de Sequência Molecular
População Rural
Sequências Repetidas Terminais/genética
 
Editor
Mary Ann Liebert, Inc
Referência
REGO, F. F. de A. et al. HTLV type 1 molecular study in Brazilian villages with African characteristics giving support to the post-Columbian introduction hypothesis. AIDS Research and Human Retroviruses, v. 24, n. 5, p. 673-677, 2008.
ISSN
1931-8405