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PUERPERAL BRAIN CRYPTOCOCCOMA IN AN HIV-NEGATIVE WOMAN
Hagan, José Edward et al. | Fecha del documento: 2014
Autor
Hagan, José Edward
Dias, Jesângeli Sousa
Villasbôas Bisneto, José Caetano
Falcão, Melissa Barreto
Ko, Albert Icksang
Ribeiro, Guilherme de Sousa
Afiliación
Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, CT, USA / Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
Hospital Couto Maia. Secretaria de Saúde do Estado da Bahia. Salvador, BA, Brasil / Universidade Federal da Bahia. Faculdade de Medicina da Bahia. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
Hospital Couto Maia. Secretaria de Saúde do Estado da Bahia. Salvador, BA, Brasil
Yale School of Public Health. Department of Epidemiology of Microbial Diseases. New Haven, CT, USA / Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisa Gonçalo Moniz. Salvador, BA, Brasil / Universidade Federal da Bahia. Instituto de Saúde Coletiva. Salvador, BA, Brasil
Resumen en ingles
Cryptococcus spp. cerebral abscesses are uncommon in immunocompetent subjects. The recommended induction treatment is the administration of amphotericin B plus fl ucytosine combined with resection for lesions ≥3cm. In this paper, we describe an HIV-negative woman diagnosed with a large cryptococcoma in the immediate postpartum period. The lesion was not resected, and due to amphotericin B intolerance, she received an extended course of fl uconazole monotherapy. There was no disease recurrence during the 4 years of follow-up. The abrupt onset of her symptoms following delivery suggests that she developed a postpartum immune reconstitution syndrome. This case also demonstrates that in specifi c situations fl uconazole monotherapy can be attempted in immunocompetent patients with cryptococcoma
Palabras clave en ingles
Cryptococcus
Immune reconstitution inflammatory syndrome
Treatment
 
Editor
Sociedade Brasileira de Medicina Tropical
Referencia
HAGAN, J. E. et al. Puerperal brain cryptococcoma in an HIV-negative woman. Revista da Sociedade Brasileira de Medicina Tropical, v. 47, n. 2, p. 254-256, 2014.
DOI
10.1590/0037-8682-0215-2013
ISSN
0037-8682