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ASSOCIATION BETWEEN SLEEP DURATION AND ALL-CAUSE MORTALITY IN OLD AGE: 9-YEAR FOLLOW-UP OF THE BAMBUı´ COHORT STUDY, BRAZIL
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Oswaldo Cruz Foundation. Rene Rachou Research Institute. Belo Horizonte, MG, Brazil / Kings College London, Institute of Psychiatry. Health Service and Population Research. Section of Epidemiology. London, UK.
Kings College London, Institute of Psychiatry. Health Service and Population Research. Section of Epidemiology. London, UK.
Kings College London, Institute of Psychiatry. Health Service and Population Research. Section of Epidemiology. London, UK.
Oswaldo Cruz Foundation. Rene Rachou Research Institute. Belo Horizonte, MG, Brazil.
Oswaldo Cruz Foundation. Rene Rachou Research Institute. Belo Horizonte, MG, Brazil.
Instituto de Previdencia dos Servidores do Estado de Minas Gerais. Department of Psychiatry. Belo Horizonte, MG, Brazil.
Kings College London, Institute of Psychiatry. Health Service and Population Research. Section of Epidemiology. London, UK
Oswaldo Cruz Foundation. Rene Rachou Research Institute. Belo Horizonte, MG, Brazil / Federal University of Minas Gerais. Medical School. Belo Horizonte, MG, Brazil.
Kings College London, Institute of Psychiatry. Health Service and Population Research. Section of Epidemiology. London, UK.
Kings College London, Institute of Psychiatry. Health Service and Population Research. Section of Epidemiology. London, UK.
Kings College London, Institute of Psychiatry. Health Service and Population Research. Section of Epidemiology. London, UK.
Oswaldo Cruz Foundation. Rene Rachou Research Institute. Belo Horizonte, MG, Brazil.
Oswaldo Cruz Foundation. Rene Rachou Research Institute. Belo Horizonte, MG, Brazil.
Instituto de Previdencia dos Servidores do Estado de Minas Gerais. Department of Psychiatry. Belo Horizonte, MG, Brazil.
Kings College London, Institute of Psychiatry. Health Service and Population Research. Section of Epidemiology. London, UK
Oswaldo Cruz Foundation. Rene Rachou Research Institute. Belo Horizonte, MG, Brazil / Federal University of Minas Gerais. Medical School. Belo Horizonte, MG, Brazil.
Kings College London, Institute of Psychiatry. Health Service and Population Research. Section of Epidemiology. London, UK.
Resumen en ingles
This study investigates the association of sleep duration with risk of all-cause mortality among elderly Brazilians using data from a 9-year population-based cohort study and applying a multivariable longitudinal categorical and continuous analysis using Coxs proportional hazards models. This analysis used data from the Bambui Health and Ageing Study (BHAS), conducted in Bambuı´ city (approximately 15 000 inhabitants) in southeastern Brazil. The study population comprised 1512 (86.8%) of all eligible 1742 elderly residents. In multivariable analysis, using sleep duration as categorical variable and controlling for multiple measures of sociodemographic and health status, those who slept 9 h or more per night were found to be at higher risk of mortality than those Who slept 7 h [hazard ratio (HR): 1.53; 95% confidence interval (CI): 1.12–2.09]. Excluding those whose deaths occurred within 2 years after entry, this association remained significant (HR: 1.56; 95% CI: 1.12–2.18). In analyses using sleep duration as a continuous variable, a linear correlationwas found between sleep duration andmortality in all adjusted models in the whole sample (HR: 1.08; 95% CI: 1.02–1.15) and following exclusion of those whose deaths occurred within 2 years after entry (HR: 1.13; 95% CI: 1.06–1.21). Both linear and quadratic terms were significant, reflecting a predicted relationship, with mortality predominantly increasing in association with long sleep duration but with the addition of a slight decrease in association with shorter sleep duration. In conclusion, long rather than short sleep duration was associated principally with all-causemortality in this sample. It is therefore reasonable to suggest that clinicians should be aware of the potential adverse prognosis associated with prolonged sleep.
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