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A PEPTIDE DATASET FOR TARGET ANALYSIS OF HUMAN COMPLEMENT SYSTEM PROTEINS
Chromatography, Liquid
Tandem Mass Spectrometry
Complement System Proteins
Human serum
Cromatografía Liquida
Espectrometría de Masas en Tándem
Proteínas del Sistema Complemento
Cromatografia Líquida
Espectrometria de Massas em Tandem
Proteínas do Sistema Complemento
Sérica Humana
Autor
Afiliación
Resumen en ingles
The targeted LC-MS/MS method has been widely applied for peptide quantification, offering sensibility, specificity, and reproducibility to the analysis. However, it requires the prior selection of targets, including the construction of a spectral library. Here, we present a dataset comprising peptide mass spectra for targeted LC-MS/MS method setup, applied to a set of human complement system proteins. Additionally, we selected a group of peptides and demonstrated their stability and reproducibility in quantification. This dataset is invaluable for studies aiming at the quantification of the complement system proteins by targeted LC-MS/MS, as it provides data for spectral library construction and a list of selected peptides.
Palabras clave en portugues
LC-MS/MSPalabras clave en ingles
ProteomicsChromatography, Liquid
Tandem Mass Spectrometry
Complement System Proteins
Human serum
Palabras clave
ProteómicaCromatografía Liquida
Espectrometría de Masas en Tándem
Proteínas del Sistema Complemento
DeCS
ProteômicaCromatografia Líquida
Espectrometria de Massas em Tandem
Proteínas do Sistema Complemento
Sérica Humana
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