Objectives:There is limited evidence regarding the impact of race/racism and its intersection with socioeconomic status (SES) onbreast and cervical cancer, the two most common female cancersglobally. We investigated racial inequalities in breast and cervicalcancer mortality and whether SES (education and householdconditions) interacted with race/ethnicity.Design:The 100 Million Brazilian Cohort data were linked to theBrazilian Mortality Database, 2004–2015 (n = 20,665,005 adultwomen). We analysed the association between self-reported race/ethnicity (White/‘Parda’(Brown)/Black/Asian/Indigenous) andcancer mortality using Poisson regression, adjusting for age,calendar year, education, household conditions and area ofresidence. Additive and multiplicative interactions were assessed.Results:Cervicalcancermortalityrateswerehigher amongIndigenous(adjusted Mortality rate ratio = 1.80, 95%CI 1.39–2.33), Asian (1.63, 1.20–2.22),‘Parda’(Brown) (1.27, 1.21–1.33) and Black (1.18, 1.09–1.28)women vs White women. Breast cancer mortality rates were higheramong Black (1.10, 1.04–1.17) vs White women. Racial inequalities incervical cancer mortality were larger among women of poor household conditions, and low education (P for multiplicativeinteraction <0.001, and 0.02, respectively). Compared to Whitewomen living in completely adequate (3–4) household conditions,the risk of cervical cancer mortality in Black women with 3–4, 1–2,and none adequate conditions was 1.10 (1.01–1.21), 1.48 (1.28–1.71),and 2.03 (1.56–2.63), respectively (Relative excess risk due tointeraction-RERI = 0.78, 0.18–1.38). Among‘Parda’(Brown) women therisk was 1.18 (1.11–1.25), 1.68 (1.56–1.81), and 1.84 (1.63–2.08),respectively (RERI = 0.52, 0.16–0.87). Compared to high-educatedWhite women, the risk in high-, middle- and low-educated Blackwomen was 1.14 (0.83–1.55), 1.93 (1.57–2.38) and 2.75 (2.33–3.25),respectively (RERI = 0.36,−0.05–0.77). Among‘Parda’(Brown) womenthe risk was 1.09 (0.91–1.31), 1.99 (1.70–2.33) and 3.03 (2.61–3.52),respectively (RERI = 0.68, 0.48–0.88). No interactions were found forbreast cancer.Conclusion:Low SES magnified racial inequalities in cervical cancermortality. The intersection between race/ethnicity, SES and genderneeds to be addressed to reduce racial health inequalities.