This paper aims to continue a research effort, which seeks to bring together theoretical and methodological constructs developed by Birger Hjørland and Pierre Bourdieu to investigate structures of production, organization and communication of knowledge from a critical point of view, focusing on health. Paths built in the dialogue between the concepts of both authors are reclaimed and epistemological, thematic, conceptual and methodological relations are indicated. With the aim of guiding paths for the health field analysis in Brazil from the contributions of domain analysis and the sociology of knowledge, the following analytical plans are used: a) historical and institutional; b) relational; c) of production, organization and dissemination of knowledge. On a methodological plane, qualitative and interpretative tools are used, such as depth and narrative interviews, documentation analysis and direct observation, complemented by an analysis of social networks and informetrics. It is concluded that health is a complex knowledge domain, which demands domains that analysts and scholars of the scientific field handle theoretical and methodological means able to achieve its cultural, social and historical existence.