Use este identificador para citar ou linkar para este item:
Tipo de documento
ArtigoDireito Autoral
Acesso aberto
Coleções
- ICICT - Artigos de Periódicos [1382]
- IOC - Artigos de Periódicos [12791]
Metadata
Mostrar registro completo
ANTI-HUMAN IMMUNODEFICIENCY VIRUS-1 ANTIBODY TITERS IN INJECTION DRUG USERS COMPARED TO SEXUALLY INFECTED INDIVIDUALS
Autor(es)
Afiliação
Resumo em Inglês
Sera from infected injection drug users (IDU) have shown to have antibodies against synthetic human immunodeficiency virus-1 (HIV-1) envelope peptides more frequently. In this study, reactivity of 48 IDU plasma were compared to 60 plasmas obtained from sexually infected individuals (S). The overall reactivity of plasma from IDU compared to S was higher, and the reactivity titers were much higher for IDU plasma than S. IDU plasma also showed a broader antibody response. The higher reactivity titers were observed mainly for the gp41 immunodominant epitope and V3 peptides corresponding to the consensus sequences of HIV-1 subtypes/variants prevalent in Brazil (B, F, C) indicating the specificity in the higher immune response of IDU.
Compartilhar