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https://www.arca.fiocruz.br/handle/icict/51548
ECONOMIC EVALUATIONS ADDRESSING DIAGNOSIS AND TREATMENT STRATEGIES FOR NEGLECTED TROPICAL DISEASES: AN OVERVIEW
Affilliation
Fundação Oswaldo Cruz. Instituto René Rachou. Pesquisa Clínica e Políticas Públicas em Doenças Infecciosas e Parasitárias. Belo Horizonte, MG, Brazil/Federal de Educação Tecnológica de Minas Gerais. Contagem, MG, Brazil.
Fundação Oswaldo Cruz. Instituto René Rachou. Pesquisa Clínica e Políticas Públicas em Doenças Infecciosas e Parasitárias. Belo Horizonte, MG, Brazil.
Fundação Oswaldo Cruz. Instituto René Rachou. Pesquisa Clínica e Políticas Públicas em Doenças Infecciosas e Parasitárias. Belo Horizonte, MG, Brazil.
Fundação Oswaldo Cruz. Instituto René Rachou. Pesquisa Clínica e Políticas Públicas em Doenças Infecciosas e Parasitárias. Belo Horizonte, MG, Brazil.
Fundação Oswaldo Cruz. Instituto René Rachou. Pesquisa Clínica e Políticas Públicas em Doenças Infecciosas e Parasitárias. Belo Horizonte, MG, Brazil.
Abstract
Neglected tropical diseases (NTDs) are those affecting vulnerable people and causing
additional social and economic burden. The aim of this study was to carry out a general
overview of the health economic assessments involving the diagnosis and treatment of six
NTDs: cutaneous leishmaniasis (CL), Chagas disease, cysticercosis, filariasis, schistosomiasis
and visceral leishmaniasis (VL). The literature search was based on two of the main medical
literature databases (Medline and SciELO) and identified 46 studies. Twenty-six studies
(57%) addressed therapeutic strategies, while other 20 (43%) assessed diagnostic or both
diagnostic and therapeutic approaches. The studies were published between 1994 and 2021,
and 57% of them (26/46) were carried out in four countries. Cost-effectiveness analyses were
conducted in 59% (27/46) of the studies. Economic studies of NTDs have timidly increased
in recent years. Despite the improvement of analytical methods, completeness and accuracy
of information, there are few new technologies applied to NTDs and public health systems. In
addition, economic studies for NTDs are concentrated in a few countries. Thus, this review
points out the need for investment in research, development and training of human resources
dedicated to the economic analysis in health, especially on NTDs, as a strategy to reduce
inequalities by optimizing the use of health resources.
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