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https://www.arca.fiocruz.br/handle/icict/50491
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ArtigoDireito Autoral
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- ENSP - Artigos de Periódicos [2326]
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ALCOHOL DRINKING AND HEAD AND NECK CANCER RISK: THE JOINT EFFECT OF INTENSITY AND DURATION
Autor(es)
Di Credico, Gioia
Polesel, Jerry
Dal Maso, Luigino
Pauli, Francesco
Torelli, Nicola
Luce, Daniele
Radoï, Loredana
Matsuo, Keitaro
Serraino, Diego
Brennan, Paul
Holcatova, Ivana
Ahrens, Wolfgang
Lagiou, Pagona
Canova, Cristina
Richiardi, Lorenzo
M Healy, Claire
Kjaerheim, Kristina
Conway, David I
Macfarlan, Gary J
Thomson, Peter
Agudo, Antonio
Znaor, Ariana
Franceschi, Silvia
Herrero, Rolando
Toporcov, Tatiana N
Moyses, Raquel A
Muscat, Joshua
Negri, Eva
Vilensky, Marta
Fernandez, Leticia
Curado, Maria Paula
Menezes, Ana
Daudt, Alexander W
Koifman, Rosalina
Wunsch-Filho, Victor
Olshan, Andrew F
Zevallos, Jose P
Sturgis, Erich M
Li, Guojun
Levi, Fabio
Zhang, Zuo-Feng
Morgenstern, Hal
Smith, Elaine
Lazarus, Philip
La Vecchia, Carlo
Garavello, Werner
Chen, Chu
Schwartz, Stephen M
Zheng, Tongzhang
Vaughan, Thomas L
Kelsey, Karl
McClean, Michael
Benhamou, Simone
Hayes, Richard B
Purdue, Mark P
Gillison, Maura
Schantz, Stimson
Yu, Guo-Pei
Chuang, Shu-Chun
Boffetta, Paolo
Hashibe, Mia
Yuan-Chin, Amy Lee
Edefonti, Valeria
Polesel, Jerry
Dal Maso, Luigino
Pauli, Francesco
Torelli, Nicola
Luce, Daniele
Radoï, Loredana
Matsuo, Keitaro
Serraino, Diego
Brennan, Paul
Holcatova, Ivana
Ahrens, Wolfgang
Lagiou, Pagona
Canova, Cristina
Richiardi, Lorenzo
M Healy, Claire
Kjaerheim, Kristina
Conway, David I
Macfarlan, Gary J
Thomson, Peter
Agudo, Antonio
Znaor, Ariana
Franceschi, Silvia
Herrero, Rolando
Toporcov, Tatiana N
Moyses, Raquel A
Muscat, Joshua
Negri, Eva
Vilensky, Marta
Fernandez, Leticia
Curado, Maria Paula
Menezes, Ana
Daudt, Alexander W
Koifman, Rosalina
Wunsch-Filho, Victor
Olshan, Andrew F
Zevallos, Jose P
Sturgis, Erich M
Li, Guojun
Levi, Fabio
Zhang, Zuo-Feng
Morgenstern, Hal
Smith, Elaine
Lazarus, Philip
La Vecchia, Carlo
Garavello, Werner
Chen, Chu
Schwartz, Stephen M
Zheng, Tongzhang
Vaughan, Thomas L
Kelsey, Karl
McClean, Michael
Benhamou, Simone
Hayes, Richard B
Purdue, Mark P
Gillison, Maura
Schantz, Stimson
Yu, Guo-Pei
Chuang, Shu-Chun
Boffetta, Paolo
Hashibe, Mia
Yuan-Chin, Amy Lee
Edefonti, Valeria
Afiliação
University of Trieste. Department of Economics, Business, Mathematics and Statistics. Trieste, Italy.
Centro di Riferimento Oncologico di Aviano. Cancer Epidemiology Unit. Aviano, Italy.
Centro di Riferimento Oncologico di Aviano. Cancer Epidemiology Unit. Aviano, Italy.
University of Trieste. Department of Economics, Business, Mathematics and Statistics. Trieste, Italy.
University of Trieste. Department of Economics, Business, Mathematics and Statistics. Trieste, Italy.
Université de Rennes. Pointe-à-Pitre, France.
Centre for Research in Epidemiology and Population Health. Villejuif, France.
Aichi Cancer Center Research Institute. Nagoya, Japan / Nagoya University Graduate School of Medicine. Nagoya, Japan.
Centro di Riferimento Oncologico di Aviano. Cancer Epidemiology Unit. Aviano, Italy.
International Agency for Research on Cancer. Lyon, France.
Charles University. Institute of Hygiene & Epidemiology. Prague, Czech Republic.
Leibniz Institute for Prevention Research and Epidemiology. Bremen, Germany / University of Bremen. Faculty of Mathematics and Computer Science. Bremen, Germany.
National and Kapodistrian University of Athens. Athens, Greece.
University of Padua. Padova, Italy.
University of Turin. Turin, Italy.
Trinity College School of Dental Science. Dublin, Ireland.
Cancer Registry of Norway. Oslo, Norway.
University of Glasgow. Glasgow, UK.
University of Aberdeen. Aberdeen, UK.
University of Hong Kong. Hong Kong, China.
L'Hospitalet de Llobregat. Barcelona, Spain.
International Agency for Research on Cancer, Lyon, France.
Centro di Riferimento Oncologico di Aviano. Aviano, Italy.
International Agency for Research on Cancer, Lyon, France.
Universidade de São Paulo. São Paulo, Brasil.
Universidade de São Paulo. São Paulo, Brasil.
Penn State College of Medicine. Hershey, PA, USA.
University of Milan. Milan, Italy.
Universidad de Buenos Aires. Buenos Aires, Argentina.
Institute of Oncology and Radiobiology. Havana, Cuba.
A.C.Camargo Cancer Center. São Paulo, SP, Brasil.
Universidade Federal de Pelotas. Pelotas, RS, Brasil.
Hospital Moinhos de Vento. Porto Alegre, RS, Brasil
Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Rio de Janeiro, RJ, Brasil.
Universidade de São Paulo. São Paulo, Brasil.
Gillings School of Global Public Health. Chapel Hill, NC, USA.
Washington University School of Medicine. St Louis, MO, USA.
Baylor College of Medicine. Houston, Texas, USA.
Baylor College of Medicine. Houston, Texas, USA.
University of Lausanne. Lausanne, Switzerland.
UCLA School of Public Health. Los Angeles, CA, USA.
University of Michigan. Ann Arbor, MI, USA.
University of Iowa. Iowa City, IA, USA.
Washington State University. Spokane, WA, USA.
Università degli Studi di Milano. Milano, Italy.
University of Milano-Bicocca. Monza, Italy.
Fred Hutchinson Cancer Research Center. Seattle, WA, USA.
Fred Hutchinson Cancer Research Center. Seattle, WA, USA.
Brown University School of Public Health. Providence, RI, USA.
Fred Hutchinson Cancer Research Center. Seattle, WA, USA.
Brown University School of Public Health. Providence, RI, USA.
Boston University School of Public Health. Boston, MA, USA.
National Institute of Health and Medical Research. Villejuif, France.
New York University School Of Medicine, New York, NY, USA.
National Cancer Institute. Bethesda, MD, USA.
University of Texas. Houston, TX, USA.
New York Eye and Ear Infirmary. New York, NY, USA.
Peking University. Beijing, China.
National Health Research Institutes. Miaoli, Taiwan.
University of Bologna. Bologna, Italy / Icahn School of Medicine at Mount Sinai. New York, NY, USA.
University of Utah School of Medicine and Huntsman Cancer Institute. Salt Lake City, UT, USA.
University of Utah School of Medicine and Huntsman Cancer Institute. Salt Lake City, UT, USA.
Università degli Studi di Milano. Milano, Italy.
Centro di Riferimento Oncologico di Aviano. Cancer Epidemiology Unit. Aviano, Italy.
Centro di Riferimento Oncologico di Aviano. Cancer Epidemiology Unit. Aviano, Italy.
University of Trieste. Department of Economics, Business, Mathematics and Statistics. Trieste, Italy.
University of Trieste. Department of Economics, Business, Mathematics and Statistics. Trieste, Italy.
Université de Rennes. Pointe-à-Pitre, France.
Centre for Research in Epidemiology and Population Health. Villejuif, France.
Aichi Cancer Center Research Institute. Nagoya, Japan / Nagoya University Graduate School of Medicine. Nagoya, Japan.
Centro di Riferimento Oncologico di Aviano. Cancer Epidemiology Unit. Aviano, Italy.
International Agency for Research on Cancer. Lyon, France.
Charles University. Institute of Hygiene & Epidemiology. Prague, Czech Republic.
Leibniz Institute for Prevention Research and Epidemiology. Bremen, Germany / University of Bremen. Faculty of Mathematics and Computer Science. Bremen, Germany.
National and Kapodistrian University of Athens. Athens, Greece.
University of Padua. Padova, Italy.
University of Turin. Turin, Italy.
Trinity College School of Dental Science. Dublin, Ireland.
Cancer Registry of Norway. Oslo, Norway.
University of Glasgow. Glasgow, UK.
University of Aberdeen. Aberdeen, UK.
University of Hong Kong. Hong Kong, China.
L'Hospitalet de Llobregat. Barcelona, Spain.
International Agency for Research on Cancer, Lyon, France.
Centro di Riferimento Oncologico di Aviano. Aviano, Italy.
International Agency for Research on Cancer, Lyon, France.
Universidade de São Paulo. São Paulo, Brasil.
Universidade de São Paulo. São Paulo, Brasil.
Penn State College of Medicine. Hershey, PA, USA.
University of Milan. Milan, Italy.
Universidad de Buenos Aires. Buenos Aires, Argentina.
Institute of Oncology and Radiobiology. Havana, Cuba.
A.C.Camargo Cancer Center. São Paulo, SP, Brasil.
Universidade Federal de Pelotas. Pelotas, RS, Brasil.
Hospital Moinhos de Vento. Porto Alegre, RS, Brasil
Fundação Oswaldo Cruz. Escola Nacional de Saúde Pública Sergio Arouca. Rio de Janeiro, RJ, Brasil.
Universidade de São Paulo. São Paulo, Brasil.
Gillings School of Global Public Health. Chapel Hill, NC, USA.
Washington University School of Medicine. St Louis, MO, USA.
Baylor College of Medicine. Houston, Texas, USA.
Baylor College of Medicine. Houston, Texas, USA.
University of Lausanne. Lausanne, Switzerland.
UCLA School of Public Health. Los Angeles, CA, USA.
University of Michigan. Ann Arbor, MI, USA.
University of Iowa. Iowa City, IA, USA.
Washington State University. Spokane, WA, USA.
Università degli Studi di Milano. Milano, Italy.
University of Milano-Bicocca. Monza, Italy.
Fred Hutchinson Cancer Research Center. Seattle, WA, USA.
Fred Hutchinson Cancer Research Center. Seattle, WA, USA.
Brown University School of Public Health. Providence, RI, USA.
Fred Hutchinson Cancer Research Center. Seattle, WA, USA.
Brown University School of Public Health. Providence, RI, USA.
Boston University School of Public Health. Boston, MA, USA.
National Institute of Health and Medical Research. Villejuif, France.
New York University School Of Medicine, New York, NY, USA.
National Cancer Institute. Bethesda, MD, USA.
University of Texas. Houston, TX, USA.
New York Eye and Ear Infirmary. New York, NY, USA.
Peking University. Beijing, China.
National Health Research Institutes. Miaoli, Taiwan.
University of Bologna. Bologna, Italy / Icahn School of Medicine at Mount Sinai. New York, NY, USA.
University of Utah School of Medicine and Huntsman Cancer Institute. Salt Lake City, UT, USA.
University of Utah School of Medicine and Huntsman Cancer Institute. Salt Lake City, UT, USA.
Università degli Studi di Milano. Milano, Italy.
Resumo em Inglês
BACKGROUND: Alcohol is a well-established risk factor for head and neck cancer (HNC). This study aims to explore the effect of
alcohol intensity and duration, as joint continuous exposures, on HNC risk. METHODS: Data from 26 case-control studies in the INHANCE Consortium were used, including never and current drinkers who drunk ≤10 drinks/day for ≤54 years (24234 controls, 4085 oral cavity, 3359 oropharyngeal, 983 hypopharyngeal and 3340 laryngeal
cancers). The dose-response relationship between the risk and the joint exposure to drinking intensity and duration was
investigated through bivariate regression spline models, adjusting for potential confounders, including tobacco smoking.
RESULTS: For all subsites, cancer risk steeply increased with increasing drinks/day, with no appreciable threshold effect at lower
intensities. For each intensity level, the risk of oral cavity, hypopharyngeal and laryngeal cancers did not vary according to years of
drinking, suggesting no effect of duration. For oropharyngeal cancer, the risk increased with durations up to 28 years, flattening
thereafter. The risk peaked at the higher levels of intensity and duration for all subsites (odds ratio = 7.95 for oral cavity, 12.86 for
oropharynx, 24.96 for hypopharynx and 6.60 for larynx). CONCLUSIONS: Present results further encourage the reduction of alcohol intensity to mitigate HNC risk.
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