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ArtículoDerechos de autor
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Fecha del embargo
2022-01-01
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- IOC - Artigos de Periódicos [12642]
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EMERGING CHAGAS DISEASE IN AMAZONIAN BRAZIL
Autor
Afiliación
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Medicina Tropical. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Medicina Tropical. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Medicina Tropical. Rio de Janeiro, RJ. Brasil.
Fundação Nacional de Saúde. Instituto Evandro Chagas. Belém, PA, Brasil.
London School of Hygiene and Tropical Medicine. Department of Infectious and Tropical Diseases. London, UK.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Medicina Tropical. Rio de Janeiro, RJ. Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Medicina Tropical. Rio de Janeiro, RJ. Brasil.
Fundação Nacional de Saúde. Instituto Evandro Chagas. Belém, PA, Brasil.
London School of Hygiene and Tropical Medicine. Department of Infectious and Tropical Diseases. London, UK.
Resumen en ingles
In the Amazon Basin,Trypanosoma cruzi infection is enzootic, involving a
variety of wild mammals and at least 10 of the 16 reported silvatic triatomine
bug species. Human cases of Chagas disease are increasing, indicating that
the disease may be emerging as a wider public health problem in the region:
38 cases from 1969 to 1992, and 167 in the past eight years. This article reviews
the status of Chagas disease in Amazonian Brazil, including known reservoirs
and vectors, and the genetic diversity of T. cruzi. At least three subspecific
groups of T. cruzi – T. cruzi I Z1,T. cruzi Z3 and T. cruzi Z3/Z1 ASAT – are present.
It appears that T. cruzi I has an extant capacity for genetic exchange. Attention
is also drawn to the risk of domestic endemicity, in addition to the tasks facing
the disease control authorities.
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