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DRUG-RESISTANCE IN LEPROSY: MOVING TOWARD UNDERSTANDING THE SCOPE OF THE PROBLEM AND HOW TO TACKLE IT
Rifampicin
Dapsone
Multidrug treatment
Tuberculosis
Moraes, Milton Ozório | Fecha del documento:
2016
Autor
Afiliación
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hanseníase. Rio de Janeiro, RJ. Brasil.
Resumen en ingles
Leprosy is an infectious disease caused by Mycobacterium leprae, a bacterium that infects Schwann cells in the peripheral nervous system and macrophages in the skin. Leprosy presents primarily as a peripheral neuropathy but may lead to deformities if it progresses without treatment. Leprosy cases are classified as paucibacillary if the patient has 5 or fewer skin lesions and low bacterial counts or as multibacillary if the patient has more than 5 lesions and high bacterial counts. The complexity of clinical presentations has hindered the development of an easy diagnostic test.
Palabras clave en ingles
Antimicrobial resistanceRifampicin
Dapsone
Multidrug treatment
Tuberculosis
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