Please use this identifier to cite or link to this item: https://www.arca.fiocruz.br/handle/icict/32962

Type
Article
Copyright
Open access
Embargo date
2019-11-06
Collections
Share

Statistics
Metadata
Show full item record

IN VITRO SUSCEPTIBILITIES OF ISOLATES OF SPOROTHRIX SCHENCKII TO ITRACONAZOLE AND TERBINAFINE
Kohler, L. M. et al. | Date Issued: 2004
Author
Kohler, L. M.
Monteiro, P. C. F.
Hahn, R. C.
Hamdan, J. S.
Affilliation
Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Microbiologia. Belo Horizonte, MG, Brasil.
Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil.
Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Microbiologia. Belo Horizonte, MG, Brasil.
Universidade Federal de Minas Gerais. Instituto de Ciências Biológicas. Departamento de Microbiologia. Belo Horizonte, MG, Brasil.
Abstract
Thirty isolates of the yeast form of Sporothrix schenckii were evaluated for in vitro susceptibility to itraconazole and terbinafine by the recommended NCCLS modified technique (M27-A2). The MICs of itraconazole obtained oscillated between 0.062 and 4.0 g/ml, and those of terbinafine oscillated between 0.007 and 0.50 g/ml; therefore, terbinafine showed greater in vitro activity.
Keywords
Sporothrix schenckii
Itraconazole
Terbinafine
 
Publisher
American Society for Microbiology
Citation
KOHLER, Lidiane Meire et al. In Vitro Susceptibilities of Isolates of Sporothrix schenckii to itraconazole and terbinafine. Journal of Clinical Microbiology, v. 42, n. 9, p. 4319-4320, Sept. 2004.
DOI
10.1128/JCM.42.9.4319-4320.2004
ISSN
0095-1137