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2030-01-01
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- IOC - Artigos de Periódicos [12642]
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MOLECULAR CHARACTERISTICS OF EXTENDEDSPECTRUM B-LACTAMASE-PRODUCING ESCHERICHIA COLI FROM RIO DE JANEIRO, BRAZIL
caracterização molecular
b-lactamase de espectro alargado
Rio de Janeiro
molecular characterization
extended-spectrum b-lactamase
Rio de Janeiro
Afiliación
Calgary Laboratory Services. Division of Microbiology. Calgary, AB. Canada / University of Calgary. Department of Pathology & Laboratory Medicine. Calgary, AB, Canada.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Infecção Hospitalar. Rio de Janeiro, RJ, Brasil.
Universidade de São Paulo. Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Departamento de Análises Clínicas, Toxicológicas e Bromatológicas. Ribeirão Preto, SP, Brasil.
Calgary Laboratory Services. Division of Microbiology. Calgary, AB. Canada / University of Calgary. Department of Pathology & Laboratory Medicine. Calgary, AB, Canada / University of Calgary. Microbiology and Infectious Diseases. Calgary, AB, Canada.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Pesquisa em Infecção Hospitalar. Rio de Janeiro, RJ, Brasil.
Universidade de São Paulo. Faculdade de Ciências Farmacêuticas de Ribeirão Preto. Departamento de Análises Clínicas, Toxicológicas e Bromatológicas. Ribeirão Preto, SP, Brasil.
Calgary Laboratory Services. Division of Microbiology. Calgary, AB. Canada / University of Calgary. Department of Pathology & Laboratory Medicine. Calgary, AB, Canada / University of Calgary. Microbiology and Infectious Diseases. Calgary, AB, Canada.
Resumen en ingles
Twenty-five extended-spectrum b-lactamase (ESBL)-producing Escherichia coli clinical isolates from Rio de Janeiro, Brazil were characterized by isoelectric focusing, PCR and sequencing of blaESBL genes, plasmid-mediated quinolone resistance determinants, phylogenetic groups, replicon typing, pulsed-field electrophoresis, and multilocus sequencing typing. Twenty-three (92%) ESBL-producing E. coli isolates were positive for blaCTX-M genes, aac(6¢)-Ib-cr, and qnrB. Genetic relatedness of ESBL producers clustered seven (28%) CTX-M-15-producing isolates as sequence type (ST)410, clonal complex (CC) 23, and two (8%) as clone O25-ST131. Our results illustrate the predominance of phylogroup A (52%), ST410 (CC 23) and CTX-M-15 among ESBLproducing E. coli isolates from hospitals in Rio de Janeiro.
Palabras clave en portugues
Escherichia colicaracterização molecular
b-lactamase de espectro alargado
Rio de Janeiro
Palabras clave en ingles
Escherichia colimolecular characterization
extended-spectrum b-lactamase
Rio de Janeiro
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