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https://www.arca.fiocruz.br/handle/icict/27992
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ArtigoDireito Autoral
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2050-01-01
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TRICHOPHYTON SPECIES SUSCEPTIBILITY TO GREEN AND RED PROPOLIS FROM BRAZIL
Própolis verde brasileira
dermatófito
Própolis vermelha brasileira
Trichophyton sp
Brazilian green propolis
Brazilian red propolis
dermatophyte
Trichophyton sp
Brasil
Itraconazol / farmacologia
Testes de Sensibilidade Microbiana
Viabilidade Microbiana
Naftalenos / farmacologia
Própolis / farmacologia
Trichophyton / efeitos de drogas
Autor(es)
Afiliação
Federal University of Pernambuco (UFPE). Department of Mycology. Recife, PE, Brazil / Keizo Asami Immunopathology Laboratory (LIKA ⁄ UFPE). Recife, PE, Brazil.
Federal University of Pernambuco (UFPE). Department of Mycology. Recife, PE, Brazil / Keizo Asami Immunopathology Laboratory (LIKA ⁄ UFPE). Recife, PE, Brazil.
Federal University of Pernambuco (UFPE). Department of Mycology. Recife, PE, Brazil.
Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.
Pharma Néctar. Belo Horizonte, MG, Brazil.
Federal University of Pernambuco (UFPE). Department of Mycology. Recife, PE, Brazil.
Federal University of Pernambuco (UFPE). Department of Mycology. Recife, PE, Brazil.
Keizo Asami Immunopathology Laboratory (LIKA ⁄ UFPE). Recife, PE, Brazil / Rural Federal University of Pernambuco. Department of Animal Morphology and Physiology (UFRPE). Recife, PE, Brazil.
Federal University of Pernambuco (UFPE). Department of Mycology. Recife, PE, Brazil / Keizo Asami Immunopathology Laboratory (LIKA ⁄ UFPE). Recife, PE, Brazil.
Federal University of Pernambuco (UFPE). Department of Mycology. Recife, PE, Brazil.
Fundação Oswaldo Cruz. Instituto Aggeu Magalhães. Recife, PE, Brasil.
Pharma Néctar. Belo Horizonte, MG, Brazil.
Federal University of Pernambuco (UFPE). Department of Mycology. Recife, PE, Brazil.
Federal University of Pernambuco (UFPE). Department of Mycology. Recife, PE, Brazil.
Keizo Asami Immunopathology Laboratory (LIKA ⁄ UFPE). Recife, PE, Brazil / Rural Federal University of Pernambuco. Department of Animal Morphology and Physiology (UFRPE). Recife, PE, Brazil.
Resumo em Inglês
AIMS:
The in vitro antifungal activity of Brazilian green and red propolis was tested against different species of Trichophyton.
METHODS AND RESULTS:
The antifungal activity of the Brazilian aqueous and alcoholic extracts of the green propolis and the alcoholic extract of red propolis was observed against Trichophyton rubrum, Trichophyton tonsurans and Trichophyton mentagrohytes samples, using as controls itraconazole and terbinafine. The minimal inhibitory concentration was determined following the microdilution method indicated by the 'Clinical and Laboratory Standards Institute'. The minimal fungicide concentration was determined by the absence of growth in liquid sabouraud culture medium. The data obtained showed that the green propolis alcoholic extract's antifungal activity was from 64 to 1024 microg ml(-1), whereas the red propolis alcoholic extract was from 8 to 1024 microg ml(-1).
CONCLUSIONS:
The antifungal activity of the red propolis alcoholic extract was more efficient than the green propolis alcoholic extract for all three species studied. The T. rubrum samples were shown to be more sensitive to the antifungal activity of the alcoholic extracts of the propolis.
SIGNIFICANCE AND IMPACT OF THE STUDY:
The antifungal potential of the alcoholic extracts of green and red propolis demonstrated suggest an applicable potential as an alternative treatment for dermatophytosis caused by these species.
Palavras-chave
antifúngicoPrópolis verde brasileira
dermatófito
Própolis vermelha brasileira
Trichophyton sp
Palavras-chave em inglês
antifungalBrazilian green propolis
Brazilian red propolis
dermatophyte
Trichophyton sp
DeCS
Antifúngicos / farmacologiaBrasil
Itraconazol / farmacologia
Testes de Sensibilidade Microbiana
Viabilidade Microbiana
Naftalenos / farmacologia
Própolis / farmacologia
Trichophyton / efeitos de drogas
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