Use este identificador para citar ou linkar para este item:
https://www.arca.fiocruz.br/handle/icict/23014
Tipo de documento
ArtigoDireito Autoral
Acesso restrito
Data de embargo
2030-01-01
Coleções
- IOC - Artigos de Periódicos [12642]
Metadata
Mostrar registro completo
PLATELETS: VERSATILE EFFECTOR CELLS IN HEMOSTASIS, INFLAMMATION, AND THE IMMUNE CONTINUUM
Inflamação
Imunidade Inata
Imunidade Adaptativa
Infecção
defesa do hospedeiro
Inflammation
Innate immunity
Adaptive immunity
Infection
Host defense
Afiliação
University of Utah School of Medicine. Department of Medicine. Program in Molecular Medicine. Salt Lake City, Utah, USA / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunofarmacologia. Rio de Janeiro, RJ, Brasil.
University of Utah School of Medicine. Department of Medicine. Program in Molecular Medicine. Salt Lake City, Utah, USA.
University of Utah School of Medicine. Department of Medicine. Program in Molecular Medicine. Salt Lake City, Utah, USA.
University of Utah School of Medicine. Department of Medicine. Salt Lake City, Utah, USA.
University of Utah School of Medicine. Department of Medicine. Program in Molecular Medicine. Salt Lake City, Utah, USA.
University of Utah School of Medicine. Department of Medicine. Program in Molecular Medicine. Salt Lake City, Utah, USA.
University of Utah School of Medicine. Department of Medicine. Salt Lake City, Utah, USA.
Resumo em Inglês
Platelets are chief effector cells in hemostasis. In addition, however, their specializations include activities and intercellular interactions that make them key effectors in inflammation and in the continuum of innate and adaptive immunity. This review focuses on the immune features of human platelets and platelets from experimental animals and on interactions between inflammatory, immune, and hemostatic activities of these anucleate but complex and versatile cells. The experimental findings and evidence for physiologic immune functions include previously unrecognized biologic characteristics of platelets and are paralleled by new evidence for unique roles of platelets in inflammatory, immune, and thrombotic diseases.
Palavras-chave
PlaquetasInflamação
Imunidade Inata
Imunidade Adaptativa
Infecção
defesa do hospedeiro
Palavras-chave em inglês
PlateletsInflammation
Innate immunity
Adaptive immunity
Infection
Host defense
Compartilhar