Please use this identifier to cite or link to this item:
https://www.arca.fiocruz.br/handle/icict/14914
KI-1 LARGE CELL LYMPHOMA WITH REGRESSING LESIONS IN A CHILD
Author
Affilliation
Hospital Martagão Gesteira. Department of Pathology and Pediatric Oncology. Salvador, BA, Brasil / Universidade Federal da Bahia. Departamento de Patologia. Salvador, BA, Brasil
Hospital Martagão Gesteira. Department of Pathology and Pediatric Oncology. Salvador, BA, Brasil
Universidade Federal da Bahia. Departamento de Patologia. Salvador, BA, Brasil / Fundação Gonçalo Moniz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
University of Michigan. Department of Pathology. Ann Arbor, Michigan
Hospital Martagão Gesteira. Department of Pathology and Pediatric Oncology. Salvador, BA, Brasil
Universidade Federal da Bahia. Departamento de Patologia. Salvador, BA, Brasil / Fundação Gonçalo Moniz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
University of Michigan. Department of Pathology. Ann Arbor, Michigan
Abstract
Abstract: An 8-year-old boy was seen with a cutaneous Ki-1 anaplastic,
large cell lymphoma with multiple lesions. Some of the lesions showed
spontaneous regression. During more than seven years of disease no
systemic involvement was observed, but recurrent, self-heal~ngle sions
did appear. Histopathologic examination of five lesions revealed a variety
of findings, from an inflammatory infiltrate to a highly anaplastic pattern.
The neoplastic cells expressed Ki-1 and leukocyte common antigens. UItrastructurally,
those cells showed ruffled indentations. The diffe~ntial
diagnosis includes microvillous malignant lymphoma. The patient has
had a four-year follow-up without relapses.
Share