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PARASITE GENOME PROJECTS AND THE TRYPANOSOMA CRUZI GENOME INITIATIVE
Afiliación
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bioquímica e Biologia Molecular. Rio de Janeiro, RJ, Brasil. Rio de Janeiro, RJ, Brasil.
Instituto de Investigaciones en Ingenieria Genetica y Biologia Molecular. INGEBICONICET, FCEyN-UBA. Buenos Aires, Argentina.
Universidade Federal de São Paulo. São Paulo, SP, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bioquímica e Biologia Molecular. Rio de Janeiro, RJ, Brasil. Rio de Janeiro, RJ, Brasil.
Instituto de Investigaciones en Ingenieria Genetica y Biologia Molecular. INGEBICONICET, FCEyN-UBA. Buenos Aires, Argentina.
Universidade Federal de São Paulo. São Paulo, SP, Brasil.
Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Bioquímica e Biologia Molecular. Rio de Janeiro, RJ, Brasil. Rio de Janeiro, RJ, Brasil.
Resumen en ingles
Since the start of the human genome project, a great number of genome projects on other “model”
organism have been initiated, some of them already completed. Several initiatives have also been started
on parasite genomes, mainly through support from WHO/TDR, involving North-South and South-South
collaborations, and great hopes are vested in that these initiatives will lead to new tools for disease
control and prevention, as well as to the establishment of genomic research technology in developing
countries. The Trypanosoma cruzi genome project, using the clone CL-Brener as starting point, has
made considerable progress through the concerted action of more than 20 laboratories, most of them in
the South. A brief overview of the current state of the project is given.
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