Please use this identifier to cite or link to this item: http://www.arca.fiocruz.br/handle/icict/9030
Title: Invasive and noninvasive correlations of B-type natriuretic peptide in patients with heart failure due to Chagas cardiomyopathy.
Authors: Vilas-Boas, Fábio
Feitosa, Gilson Soares
Soares, Milena Botelho Pereira
Pinho Filho, Joel Alves
Nascimento, Thais
Barojas, Marcos M
Andrade, Marcus Vinicius
Santos, Ricardo Ribeiro dos
Affilliation: Santa Izabel Hospital. Academic Research Department. Salvador, BA, Brasil
Santa Izabel Hospital. Academic Research Department. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Santa Izabel Hospital. Academic Research Department. Salvador, BA, Brasil
Santa Izabel Hospital. Academic Research Department. Salvador, BA, Brasil
Santa Izabel Hospital. Academic Research Department. Salvador, BA, Brasil
Santa Izabel Hospital. Academic Research Department. Salvador, BA, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil
Heart Institute of the University of São Paulo. São Paulo, SP, Brasi
Abstract: Heart failure due to Chagas cardiomyopathy (HFCC) differs from failure with other etiologies because of the occurrence of intense inflammatory infiltrate and right ventricle compromise. This article investigates correlations of B-type natriuretic peptide (BNP) levels with parameters of severity in HFCC. Twenty-eight patients and 8 normal controls underwent heart catheterization and clinical and laboratory analyses. BNP levels were higher in patients with HFCC (P<.0001) and correlated with New York Heart Association (NYHA) class; right atrial pressure; wedge pressure; cardiac output; levels of serum sodium, hemoglobin, urea, and tumor necrosis factor-alpha; and ejection fraction. Interferon-gamma and transforming growth factor-beta did not correlate with BNP level. The authors conclude that BNP levels are elevated in patients experiencing HFCC, irrespective of NYHA class, and that the occurrence of HFCC correlates with severity of disease
DeCS: Cardiomiopatia Chagásica/complicações
Insuficiência Cardíaca/etiologia
Peptídeo Natriurético Encefálico/sangue
Cateterismo Cardíaco
Estudos de Casos e Controles
Cardiomiopatia Chagásica/sangue
Cardiomiopatia Chagásica/fisiopatologia
Diástole
Tolerância ao Exercício
Feminino
Insuficiência Cardíaca/sangue
Insuficiência Cardíaca/fisiopatologia
Hemodinâmica
Humanos
Masculino
Meia-Idade
Estudos Prospectivos
Questionários
Medição de Risco
Fatores de Risco
Sistole
Issue Date: 2008
Publisher: Wiley
Citation: VILAS-BOAS, F. et al. Invasive and noninvasive correlations of B-type natriuretic peptide in patients with heart failure due to Chagas cardiomyopathy. Congestive Heart Failure, v. 14, n. 3, p. 121-126, 2008.
ISSN: 1527-5299
Copyright: open access
Appears in Collections:IGM - Artigos de Periódicos

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