Author | Rego, Filipe Ferreira de Almeida | |
Author | Alcantara, Luiz Carlos Júnior | |
Author | Moura Neto, José Pereira de | |
Author | Miranda, Aline Cristina Andrade Mota | |
Author | Pereira, Osmario de Souza | |
Author | Gonçalves, Marilda de Souza | |
Author | Castro Filho, Bernardo Galvão | |
Access date | 2014-07-15T17:38:09Z | |
Available date | 2014-07-15T17:38:09Z | |
Document date | 2008 | |
Citation | REGO, F. F. de A. et al. HTLV type 1 molecular study in Brazilian villages with African characteristics giving support to the post-Columbian introduction hypothesis. AIDS Research and Human Retroviruses, v. 24, n. 5, p. 673-677, 2008. | pt_BR |
ISSN | 1931-8405 | |
URI | https://www.arca.fiocruz.br/handle/icict/7973 | |
Language | eng | pt_BR |
Publisher | Mary Ann Liebert, Inc | pt_BR |
Rights | open access | pt_BR |
Title | HTLV type 1 molecular study in Brazilian villages with African characteristics giving support to the post-Columbian introduction hypothesis. | pt_BR |
Type | Article | pt_BR |
Abstract | We performed an HTLV epidemiological study of 986 individuals from 17 villages from the same state of Salvador,
the city with the highest HTLV-1 prevalence in Brazil. The HTLV-1 prevalence was 3.85%, 1.56%, and
1.23% in three villages. Phylogenetic analysis of the LTR region demonstrated that all positive samples analyzed
belonged to the Transcontinental subgroup of the HTLV-1 Cosmopolitan subtype. Three of the new HTLV-
1 sequences formed a well-supported clade within one of the Latin American clusters that contain a South
African sequence. This Latin American cluster that segregated from the same ancestor as the other clade contained
a Central African sequence. This ancestral relationship could support our previous report that suggests
that this subgroup was first introduced into South Africa as a result of the migration of the Bantu population
from Central Africa to Southern Africa over the past 3000 years, and afterward to Brazil during the slave trade
between the sixteenth and nineteenth centuries. | pt_BR |
Affilliation | Bahia School of Medicine and Public Health. Bahia Foundation for Development of Science. Salvador, BA, Brasil / Oswaldo Cruz Foundation. Gonçalo Moniz Research Center. Advanced Public Health Laboratory. Salvador, BA, Brasil | pt_BR |
Affilliation | Bahia School of Medicine and Public Health. Bahia Foundation for Development of Science. Salvador, BA, Brasil / Oswaldo Cruz Foundation. Gonçalo Moniz Research Center. Advanced Public Health Laboratory. Salvador, BA, Brasil | pt_BR |
Affilliation | Oswaldo Cruz Foundation. Gonçalo Moniz Research Center. Pathology and Molecular Biology Laboratory. Salvador, BA, Brasil | pt_BR |
Affilliation | swaldo Cruz Foundation. Gonçalo Moniz Research Center. Advanced Public Health Laboratory. Salvador, BA, Brasil | pt_BR |
Affilliation | Oswaldo Cruz Foundation. Gonçalo Moniz Research Center. Pathology and Molecular Biology Laboratory. Salvador, BA, Brasil | pt_BR |
Affilliation | Oswaldo Cruz Foundation. Gonçalo Moniz Research Center. Pathology and Molecular Biology Laboratory. Salvador, BA, Brasil | pt_BR |
Affilliation | Bahia School of Medicine and Public Health. Bahia Foundation for Development of Science. Salvador, BA, Brasil / Oswaldo Cruz Foundation. Gonçalo Moniz Research Center. Advanced Public Health Laboratory. Salvador, BA, Brasil | pt_BR |
DeCS | Infecções por HTLV-I/epidemiologia | pt_BR |
DeCS | Vírus 1 Linfotrópico T Humano/genética | pt_BR |
DeCS | Epidemiologia Molecular | pt_BR |
DeCS | Brasil/epidemiologia | pt_BR |
DeCS | Migração Internacional | pt_BR |
DeCS | Vírus 1 Linfotrópico T Humano/classificação | pt_BR |
DeCS | Humanos | pt_BR |
DeCS | Dados de Sequência Molecular | pt_BR |
DeCS | População Rural | pt_BR |
DeCS | Sequências Repetidas Terminais/genética | pt_BR |