Please use this identifier to cite or link to this item: http://www.arca.fiocruz.br/handle/icict/6663
Title: 13CO2 recovery fraction in expired air of septic patients under mechanical ventilation.
Authors: Martins, Maria Auxiliadora
Coletto, Francisco Antonio
Martins Filho, Olindo Assis
Marchini, Julio Sergio
Basile Filho, Aníbal
Affilliation: Universidade de São Paulo. Hospital das Clínicas. Departamento de Cirurgia e Anatomia. Centro de Terapia Intensiva. Ribeirão Preto, SP, Brasil
Universidade de São Paulo. Hospital das Clínicas. Departamento de Cirurgia e Anatomia. Centro de Terapia Intensiva. Ribeirão Preto, SP, Brasil
Fundação Oswaldo Cruz. Centro de Pesquisas René Rachou. Laboratório de Biomarcadores de Diagnóstico e Monitoração. Belo Horizonte, MG, Brasil
Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Clínica Médica. Laboratório de Espectrometria de Massa. Ribeirão Preto, SP, Brasil
Universidade de São Paulo. Hospital das Clínicas. Departamento de Cirurgia e Anatomia. Centro de Terapia Intensiva. São Paulo, SP, Brasil
Abstract: The continuous intravenous administration of isotopic bicarbonate (NaH13CO2) has been used for the determination of theretention of the 13CO2 fraction or the 13CO2 recovered in expired air. This determination is important for the calculation of substrate oxidation. The aim of the present study was to evaluate, in critically ill patients with sepsis under mechanical ventilation, the 13CO2 recovery fraction in expired air after continuous intravenous infusion of NaH 13CO2 (3.8 µmol/kg diluted in 0.9% saline in ddH2O). A prospective study was conducted on 10 patients with septic shock between the second and fifth day of sepsis evolution (APACHE II, 25.9 ± 7.4). Initially, baseline CO2 was collected and indirect calorimetry was also performed
Keywords: Recovery fraction
13CO2
Stable isotope
Septic shock
Intensive care setting
Issue Date: 2008
Citation: MARTINS, Maria Auxiliadora et al. 13CO2 recovery fraction in expired air of septic patients under mechanical ventilation. Braz J Med Biol Res . 2008, vol.41, n.7, pp. 563-570
ISSN: 1414-431X
Appears in Collections:CPqRR - Artigos de Periódicos

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