Author | Andrade, Júlia Cé de | |
Author | Cabral, Fernando | |
Author | Clemens, Frank Jorg | |
Author | Vieira, Jaqueline Leite | |
Author | Soares, Milena B. P. | |
Author | Hotza, Dachamir | |
Author | Fredel, Márcio Celso | |
Access date | 2023-10-24T13:57:55Z | |
Available date | 2023-10-24T13:57:55Z | |
Document date | 2023 | |
Citation | ANDRADE, Júlia Cé de et al. Effect of stearic acid on the mechanical and rheological properties of PLA/ HA biocomposites. Materials Today Communications, v. 35, p. 1-7, 2023. | en_US |
ISSN | 2352-4928 | en_US |
URI | https://www.arca.fiocruz.br/handle/icict/60889 | |
Sponsorship | Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq).
Fundação Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES). | en_US |
Language | eng | en_US |
Publisher | Elsevier | en_US |
Rights | open access | en_US |
Subject in Portuguese | Biocompósitos | en_US |
Subject in Portuguese | Engenharia de tecido ósseo | en_US |
Subject in Portuguese | Andaimes | en_US |
Subject in Portuguese | Ácido polilático | en_US |
Subject in Portuguese | Nano-hidroxiapatita | en_US |
Subject in Portuguese | Ácido esteárico | en_US |
Subject in Portuguese | Surfactantes biocompatíveis | en_US |
Subject in Portuguese | Modelagem de deposição fundida | en_US |
Title | Effect of stearic acid on the mechanical and rheological properties of PLA/ HA biocomposites | en_US |
Type | Article | en_US |
DOI | 10.1016/j.mtcomm.2023.106357 | |
Abstract | In this study, biocomposite filaments of polylactic acid (PLA) combined with stearic acid (SA)-coated nano-hydroxyapatite (HA) filler were prepared and characterized. These filaments were then used in material extrusion (MEX) additive manufacturing via fused deposition modeling (FDM) to create scaffolds for bone tissue engineering (BTE). Initially, HA was characterized using transmission electron microscopy (TEM), X-ray diffraction (XRD), and the Rietveld method. Particle size distribution was examined through dynamic light scattering (DLS), and its specific surface area was determined by the Brunauer-Emmett-Teller (BET) method. Subsequently, the HA nanoparticles were coated with stearic acid (SA) to explore its potential as a surfactant for PLA/HA nanocomposites. For composite fabrication, pure HA and SA-coated HA were mixed with PLA in a torque rheometer to obtain PLA/HA and PLA/HA-SA biocomposites. Their flow behavior was evaluated using a slit die rheometer, demonstrating that the SA coating improved rheological properties. The composites were extruded to produce 1.75 mm diameter filaments, which were analyzed by mechanical tensile testing, showing that the SA coating reduced the fragility of the PLA/HA filaments. The filaments exhibited high repeatability in terms of quality, facilitating scaffold printing. The FDM-manufactured scaffolds were analyzed through compressive testing, Fourier transform infrared (FTIR) spectroscopy, differential scanning calorimetry (DSC), and AlamarBlue Cell Viability Analysis. The results demonstrated that these scaffolds possess the required mechanical, thermal, and cytotoxicity properties for applications in bone tissue engineering. | en_US |
Affilliation | Federal University of Santa Catarina. Ceramic and Composite Materials Research Group. Florianopolis, SC, Brazil / Laboratory for High-Performance Ceramics. Swiss Federal Laboratories for Materials Science and Technology. Überlandstrasse, Dübendorf, Switzerland. | en_US |
Affilliation | Federal University of Santa Catarina. Ceramic and Composite Materials Research Group. Florianopolis, SC, Brazil. | en_US |
Affilliation | Laboratory for High-Performance Ceramics. Swiss Federal Laboratories for Materials Science and Technology. Überlandstrasse, Dübendorf, Switzerland | en_US |
Affilliation | Oswaldo Cruz Foundation. Gonçalo Moniz Institute. Salvador, BA, Brasil. | en_US |
Affilliation | Oswaldo Cruz Foundation. Gonçalo Moniz Institute. Salvador, BA, Brasil. | en_US |
Affilliation | Federal University of Santa Catarina. Ceramic and Composite Materials Research Group. Florianopolis, SC, Brazil / Federal University of Santa Catarina. Interdisciplinary Laboratory for the Development of Nanostructures. Florianopolis, SC, Brazil. | en_US |
Affilliation | Federal University of Santa Catarina. Ceramic and Composite Materials Research Group. Florianopolis, SC, Brazil / Federal University of Santa Catarina. Interdisciplinary Laboratory for the Development of Nanostructures. Florianopolis, SC, Brazil. | en_US |
Subject | Biocomposites | en_US |
Subject | Bone tissue engineering | en_US |
Subject | Scaffolds | en_US |
Subject | Polylactic acid | en_US |
Subject | Nano-hydroxyapatite | en_US |
Subject | Stearic acid | en_US |
Subject | Biocompatible surfactants | en_US |
Subject | Fused deposition modeling | en_US |