Please use this identifier to cite or link to this item:
https://www.arca.fiocruz.br/handle/icict/59703
Type
ArticleCopyright
Restricted access
Embargo date
2099-12-31
Collections
Metadata
Show full item record
ELECTROCARDIOGRAPHIC CHARACTERISTICS IN A POPULATION WITH HIGH RATES OF SEROPOSITIVITY FOR TRYPANOSOMA CRUZI INFECTION
Author
Affilliation
Department of Genetics. Southwest Foundation for Biomedical Research. San Antonio, TX, USA
Department of Genetics. Southwest Foundation for Biomedical Research. San Antonio, TX, USA
Department of Genetics. Southwest Foundation for Biomedical Research. San Antonio, TX, USA
Department of Genetics. Southwest Foundation for Biomedical Research. San Antonio, TX, USA
Fundação Oswaldo Cruz. Centro de Pesquisa Rene Rachou. Belo Horizonte, MGerais, Brazil
Southwest National Primate Research Center. San Antonio, TX, USA
Department of Genetics. Southwest Foundation for Biomedical Research. San Antonio, TX, USA
Department of Genetics. Southwest Foundation for Biomedical Research. San Antonio, TX, USA
Department of Genetics. Southwest Foundation for Biomedical Research. San Antonio, TX, USA
Fundação Oswaldo Cruz. Centro de Pesquisa Rene Rachou. Belo Horizonte, MGerais, Brazil
Southwest National Primate Research Center. San Antonio, TX, USA
Abstract
This study was conducted in Posse, a rural community in Goias, Brazil. Persons were recruited into the study through house-to-house sampling of all houses in the sampled area. Blood samples were collected for seropositivity assessments for Trypanosoma cruzi and an electrocardiogram was assessed using a portable system. The results demonstrate significant differences between seropositive and seronegative persons for electrocardiographic (ECG)-derived traits. Seropositive persons had substantially longer QRS and QT intervals than seronegative persons. The PR interval was significantly different between seropositive and seronegative persons. Conduction abnormalities were observed more frequently in seropositive than seronegative persons. Right bundle branch block, an ECG abnormality typical of Chagas disease, was observed in 15% of seropositive persons compared with less than 1% of seronegative persons. Results indicate that T. cruzi infection and subsequent Chagas disease will continue to be major health problems for the foreseeable future in this typical rural area of Brazil
Share