Author | Santos, Mariana Cristina Silva | |
Author | Oliveira, Guilherme Lopes de | |
Author | Mingoti, Sueli Aparecida | |
Author | Heller, Léo | |
Access date | 2023-07-18T12:34:24Z | |
Available date | 2023-07-18T12:34:24Z | |
Document date | 2023 | |
Citation | SANTOS, Mariana Cristina Silva et al. Sewerage as a protective factor for prevalence of hookworm infection in schoolchildren in Brazil: A multilevel ecological analysis of national prevalence surveys (1950-2018). The Science of the total environment, v. 895, p. 164621, 2023. doi.org/10.1016/j.scitotenv.2023.164621 | en_US |
ISSN | 1879-1026 | en_US |
URI | https://www.arca.fiocruz.br/handle/icict/59656 | |
Language | eng | en_US |
Publisher | Elsevier | en_US |
Rights | restricted access | en_US |
Title | Sewerage as a protective factor for prevalence of hookworm infection in schoolchildren in Brazil: A multilevel ecological analysis of national prevalence surveys (1950-2018). | en_US |
Type | Article | en_US |
Abstract | Introduction: The prevalence of hookworm infection in Brazil has decreased considerably in recent decades. However, there is no definitive consensus as to which changes have contributed to this reduction. A hypothesis is that improvements in environmental factors have contributed to lowering the parasite load and the level of host-parasite contact.
Methods: This is an ecological study using unbalanced panel data from two Brazilian surveys (1947-1953 and 2010-2015), with municipalities as the analysis unit. The sample comprised 1428 municipalities, in which a total of 745,983 schoolchildren aged 7 to 14 were examined. Zero-inflated Poisson regression models, with fixed and random effects were estimated to evaluate the association of potential explanatory variables with the prevalence of hookworm infection at a significance level of 5 %.
Results: We identified a significant decrease in the prevalence between the first and last analyzed periods (RR 0.096; CI 0.086-0.107); The following variables were found to have a protective effect: access to sanitary sewage systems (RR 0.984, CI 0.982-0.986), urbanization (RR 0.995, CI 0.993-0.997), and gross domestic product (RR 0.929, CI 0.912-0.945).
Conclusion: The findings of this study show a decrease in the prevalence of hookworm infections over six decades in schoolchildren in the Brazilian municipalities. Environmental, demographic, and economic factors were associated with this trend. A historical analysis indicates that interventions aimed at improving sanitation contributed to reducing the disease prevalence. | en_US |
Affilliation | Rene Rachou Institute. Oswaldo Cruz Foundation. Belo Horizonte, MG, Brazil | en_US |
Affilliation | Federal Center for Technological Education of Minas Gerais. Belo Horizonte, MG, Brazil | en_US |
Affilliation | Federal University of Minas Gerais. Belo Horizonte, MG, Brazil | en_US |
Affilliation | Rene Rachou Institute. Oswaldo Cruz Foundation. Belo Horizonte, MG, Brazil | en_US |
Subject | Brazil | en_US |
Subject | Ecological study | en_US |
Subject | Hookworm infection | en_US |
Subject | Sewerage | en_US |
Subject | Water supply | en_US |
Embargo date | 2099-01-31 | |