Author | Soares, Daniela Cristina | |
Author | Franco Filho, Luciano Chaves | |
Author | Reis, Herald Souza dos | |
Author | Rodrigues, Yan Corrêa | |
Author | Freitas, Felipe Bonfim | |
Author | Souza, Cintya de Oliveira | |
Author | Damacena, Giseli Nogueira | |
Author | Véras, Nazle Mendonça Collaço | |
Author | Gaspar, Pamela Cristina | |
Author | Benzaken, Adele Schwartz | |
Author | Favacho, Joana da Felicidade Ribeiro | |
Author | Macedo, Olinda | |
Access date | 2023-04-27T16:36:23Z | |
Available date | 2023-04-27T16:36:23Z | |
Document date | 2023 | |
Citation | SOARES, Daniela Cristina et al. Assessment of the accuracy, usability and acceptability of a rapid test for the simultaneous diagnosis of syphilis and HIV infection in a real-life scenario in the Amazon Region, Brazil. Diagnostics, v. 13, n. 4, p. 1-11, Feb. 2023. | en_US |
ISSN | 2075-4418 | |
URI | https://www.arca.fiocruz.br/handle/icict/58038 | |
Language | eng | en_US |
Publisher | MDPI | en_US |
Rights | open access | en_US |
Title | Assessment of the Accuracy, Usability and Acceptability of a Rapid Test for the Simultaneous Diagnosis of Syphilis and HIV Infection in a Real-Life Scenario in the Amazon Region, Brazil | en_US |
Type | Article | en_US |
DOI | 10.3390/diagnostics13040810 | |
Abstract | We field-assessed the accuracy, acceptability, and feasibility of the SD BIOLINE HIV/Syphilis Duo rapid diagnostic test in three groups: pregnant women, female sex workers (FSW), and men who have sex with men (MSM). Venous blood samples collected in the field were compared with the respective gold standard methods: SD BIOLINE HIV/Syphilis Duo Treponemal Test versus FTA-abs (Wama brand) treponemal laboratory test for syphilis, and SD BIOLINE HIV/Syphilis Duo Test versus the fourth generation Genscreen Ultra HIV Ag-Ag (Bio-Rad brand) laboratory test for HIV. From a total of 529 participants, 397 (75.1%) were pregnant women, 76 (14.3%) FSW and 56 (10.6%) MSM. Sensitivity and specificity parameters of HIV were 100.0% (95% CI: 82.35–100.0%) and 100.0% (95% CI: 99.28–100.0%), respectively. Sensitivity and specificity parameters found for TP antibody detection were 95.00% (95% CI: 87.69–98.62%) and 100.0% (95% CI: 98.18–100.0%), respectively. The SD BIOLINE HIV/Syphilis Duo Test showed high acceptability among participants (85.87%) and health professionals (85.51%), as well as easy usability by professionals (91.06%). The usability of the SD BIOLINE HIV/Syphilis Duo Test kit would not be a barrier to accessing rapid testing, if the product were incorporated into the list of health service supplies. | en_US |
Affilliation | Evandro Chagas Institute. Bacteriology and Mycology Section. Laboratory of Sexually Transmitted Infections. Ananindeua, PA, Brazil. | en_US |
Affilliation | Evandro Chagas Institute. Bacteriology and Mycology Section. Laboratory of Sexually Transmitted Infections. Ananindeua, PA, Brazil. | en_US |
Affilliation | Evandro Chagas Institute. Bacteriology and Mycology Section. Laboratory of Sexually Transmitted Infections. Ananindeua, PA, Brazil. | en_US |
Affilliation | Evandro Chagas Institute. Bacteriology and Mycology Section. Laboratory of Sexually Transmitted Infections. Ananindeua, PA, Brazil. | en_US |
Affilliation | Evandro Chagas Institute. Virology Section. Retrovirus Laboratory. Ananindeua. PA, Brazil. | en_US |
Affilliation | Evandro Chagas Institute. Bacteriology and Mycology Section. Laboratory of Sexually Transmitted Infections. Ananindeua, PA, Brazil. | en_US |
Affilliation | Oswaldo Cruz Foundation. Institute of Scientific and Technological Communication and Information in Health. Rio de Janeiro, RJ, Brazil. | en_US |
Affilliation | Ministry of Health. Department of Diseases of Chronic Condition and Sexually Transmitted Infections. Brasília, DF, Brazil. | en_US |
Affilliation | Ministry of Health. Department of Diseases of Chronic Condition and Sexually Transmitted Infections. Brasília, DF, Brazil. | en_US |
Affilliation | Oswaldo Cruz Foundation. Institute of Maria Leônidas e Maria Deane. Manaus, AM, Brazil / AIDS Healthcare Foudation. Los Angeles, CA, United States. | en_US |
Affilliation | Evandro Chagas Institute. Bacteriology and Mycology Section. Laboratory of Sexually Transmitted Infections. Ananindeua, PA, Brazil. | en_US |
Affilliation | Evandro Chagas Institute. Virology Section. Retrovirus Laboratory. Ananindeua. PA, Brazil. | en_US |
Affilliation | Federal University of Santa Catarina. Center for Health Sciences. Graduate Program in Pharmacy. Florianópolis, SC, Brazil. | en_US |
Subject | Amazon | en_US |
Subject | Diagnosis | en_US |
Subject | Duo test | en_US |
Subject | HIV | en_US |
Subject | Kappa coefficient | en_US |
Subject | Screening | en_US |
Subject | SD bioline duo assay | en_US |
Subject | Sensitivity | en_US |
Subject | Specificity | en_US |
Subject | Syphilis | en_US |