Author | Almeida, Antonio Eugenio Castro Cardoso de | |
Author | Filippis, Ivano de | |
Author | Ferreira, Diana Guedes | |
Author | Abreu, Alessandra Oliveira de | |
Author | Rebelo, Cristina | |
Author | Gemal, André Luis | |
Author | Marzochi, Keyla Belízia Feldman | |
Access date | 2023-03-07T14:01:41Z | |
Available date | 2023-03-07T14:01:41Z | |
Document date | 2006 | |
Citation | ALMEIDA, Antonio Eugenio Castro Cardoso de et al. Antimicrobial susceptibility of Haemophilus influenzae isolates collected from 4 centers in Brazil (1990–2003). Diagnostic Microbiology and Infectious Disease, v. 54, p. 57-62, 2006. | en_US |
ISSN | 0732-8893 | en_US |
URI | https://www.arca.fiocruz.br/handle/icict/57253 | |
Language | eng | en_US |
Publisher | Elsevier | en_US |
Rights | restricted access | en_US |
Title | Antimicrobial susceptibility of Haemophilus influenzae isolates collected from 4 centers in Brazil (1990-2003) | en_US |
Type | Article | en_US |
DOI | 10.1016/j.diagmicrobio.2005.08.001 | |
Abstract | Antimicrobial susceptibility was determined for 174 Haemophilus influenzae strains collected from patients with infection before and after vaccination against Hib (1990-1999 and 2000-2003, respectively) from 4 public health -laboratories in 3 Brazilian states. All strains were characterized for serotype and beta-lactamase production and in vitro activity of the following antimicrobial agents: -ampicillin, amoxicillin/clavulanate, ceftriaxone, rifampin, chloramphenicol, and trimethoprim/sulfamethoxazole (TMP-SMX). Minimum inhibitory concentrations were determined according to the guidelines of the National Committee for Clinical Laboratory Standards. Overall, ampicillin resistance was observed in 29 strains (17%), all beta-lactamase producers. All isolates were susceptible to amoxicillin/clavulanate and ceftriaxone. The prevalence of TMP-SMX-resistant isolates increased from 32.6% in the period 1990-1999 to 65.8% during the period 2000-2003. Among these isolates, 10.0% and 12.5% were resistant to ampicillin and chloramphenicol, respectively. Resistance to rifampin was detected in 8.2% and 9.7% of the strains, in 2 periods, respectively. Continued surveillance is necessary to monitor trends with the H. influenzae disease in Brazil. | en_US |
Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Controle da Qualidade em Saúde. Departamento de Microbiologia. Rio de Janeiro, RJ, Brazil. | en_US |
Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Controle da Qualidade em Saúde. Departamento de Microbiologia. Rio de Janeiro, RJ, Brazil. | en_US |
Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Controle da Qualidade em Saúde. Departamento de Microbiologia. Rio de Janeiro, RJ, Brazil. | en_US |
Affilliation | Secretaria Estadual de Saúde. Instituto Estadual de Infectologia S. Sebastião. Rio de Janeiro, RJ, Brazil. | en_US |
Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Controle da Qualidade em Saúde. Departamento de Microbiologia. Rio de Janeiro, RJ, Brazil. | en_US |
Affilliation | Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil. | en_US |
Subject | Haemophilus influenzae | en_US |
Subject | Antimicrobial susceptibility | en_US |
Subject | Hib vaccine | en_US |
Subject | Brazil | en_US |