Author | Oliveira, Jacqueline Ferreira de | |
Author | Ávila, Renata Eliane de | |
Author | Oliveira, Neimy Ramos de | |
Author | Sampaio, Natália da Cunha Severino | |
Author | Botelho, Maiara | |
Author | Gonçalves, Fabíola Araújo | |
Author | Ferreira Neto, Cirilo José | |
Author | Milagres, Ana Carolina de Almeida | |
Author | Gomes, Tatiane Cristina Caldeira | |
Author | Pereira, Tássia Lopardi | |
Author | Souza, Renan Pedra de | |
Author | Molina, Israel | |
Access date | 2023-01-30T16:28:48Z | |
Available date | 2023-01-30T16:28:48Z | |
Document date | 2022 | |
Citation | OLIVEIRA, Jacqueline Ferreira de et al. Persistent symptoms, quality of life, and risk factors in long COVID: a cross-sectional study of hospitalized patients in Brazil. Int J Infect Dis., v. 122, p. 1044-1051, 2022. doi: 10.1016/j.ijid.2022.07.063. | en_US |
ISSN | 1201-9712 | en_US |
URI | https://www.arca.fiocruz.br/handle/icict/56760 | |
Language | eng | en_US |
Publisher | Elsevier | en_US |
Rights | open access | en_US |
Title | Persistent symptoms, quality of life, and risk factors in long COVID: a cross-sectional study of hospitalized patients in Brazil | en_US |
Type | Article | en_US |
Abstract | Objectives: COVID-19 has been associated with long-term consequences to patient wellness and quality of life. Data on post-COVID-19 conditions are scarce in developing countries. This study aimed to investigate long COVID in a cohort of hospitalized patients in Brazil.
Methods: Surviving patients discharged from the hospital between July 1, 2020 and March 31, 2021 were assessed between 2 and 12 months after acute onset of COVID-19. The outcomes were the prevalence of persistent symptoms, risk factors associated with long COVID, and quality of life as assessed by the EuroQol 5D-3L questionnaire.
Results: Of 439 participants, most (84%) reported at least one long COVID symptom, at a median of 138 days (interquartile range [IQR] 90-201) after disease onset. Fatigue (63.1%), dyspnea (53.7%), arthralgia (56.1%), and depression/anxiety (55.1%) were the most prevalent symptoms. In multivariate analysis, dysgeusia (odds ratio [OR] 2.0, 95% confidence interval [CI] 1.18-3.44, P <0.001) and intensive care unit (ICU) admission (OR 2.6, 95% CI 1.19-6.56, P = 0.03) were independently associated with long COVID. Fifty percent of patients reported a worsened clinical condition and quality of life.
Conclusion: Long-term outcomes of SARS-CoV-2 infection in a low- to middle-income country were relevant. Fatigue was the most common persistent symptom. ICU admission was an independent factor associated with long COVID. Dysgeusia could be a potential predictor of long COVID. | en_US |
Affilliation | Infectious Disease Division. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, Brazil | en_US |
Affilliation | Infectious Disease Division. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, Brazil | en_US |
Affilliation | Critical Care Unit. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, Brazil | en_US |
Affilliation | Critical Care Unit. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, Brazil | en_US |
Affilliation | Epidemiology Division. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, Brazil | en_US |
Affilliation | Epidemiology Division. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, Brazil | en_US |
Affilliation | Infectious Disease Division. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, Brazil | en_US |
Affilliation | Infectious Disease Division. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, Brazil | en_US |
Affilliation | Critical Care. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, Brazil | en_US |
Affilliation | Infectious Disease Division. Eduardo de Menezes Hospital. Fundação Hospitalar do Estado de Minas Gerais. Belo Horizonte, MG, Brazil | en_US |
Affilliation | Integrative Biology Laboratory. Genetics, Ecology and Evolution Department. Biological Science Institute. Federal University of Minas Gerais. Belo Horizonte, MG, Brazil | en_US |
Affilliation | InsRené Rachou Institute. Oswaldo Cruz Foundation. Belo Horizonte, MG, Brazil | en_US |
Subject | Brazil | en_US |
Subject | COVID-19 | en_US |
Subject | Dysgeusia | en_US |
Subject | Long COVID | en_US |
Subject | Quality of life | en_US |
Subject | Risk factors | en_US |