Author | Ko, Albert Icksang | |
Author | Reis, Joice Neves | |
Author | Coppola, Steven J | |
Author | Gouveia, Edilane Lins | |
Author | Cordeiro, Soraia Machado | |
Author | Lôbo, Tatiana Silva | |
Author | Pinheiro, Ricardo M | |
Author | Salgado, Kátia M | |
Author | Dourado, Cibele Maria Ribeiro | |
Author | Tavares Neto, José | |
Author | Rocha, Heonir | |
Author | Reis, Mitermayer Galvão dos | |
Author | Johnson Junior, Warren D | |
Author | Riley, Lee Woodland | |
Access date | 2012-10-04T21:25:39Z | |
Available date | 2012-10-04T21:25:39Z | |
Document date | 2000 | |
Citation | KO, A.I. et al. Clonally related penicillin-nonsusceptible Streptococcus pneumoniae serotype 14 from cases of meningitis in Salvador, Brazil. Clinical Infectious of Diseases, v. 30, n. 1, p. 78-86, jan. 2000. | pt_BR |
ISSN | 1058-4838 | |
URI | https://www.arca.fiocruz.br/handle/icict/5647 | |
Language | eng | pt_BR |
Rights | open access | |
Title | Clonally related penicillin-nonsusceptible Streptococcus pneumoniae serotype 14 from cases of meningitis in Salvador, Brazil. | pt_BR |
Type | Article | pt_BR |
Abstract | Active hospital-based surveillance in the city of Salvador, Brazil, from December 1995 through October 1998, identified 221 patients with confirmed pneumococcal meningitis. Of these 221 patients, 29 (13%) had isolates with intermediate-level resistance to penicillin. Infection with these penicillin-nonsusceptible isolates was significantly associated with age of <2 years (P<.0019), previous antibiotic use (P<.0006), and coresistance to trimethoprim-sulfamethoxazole (P<.0000). Serotype 14 was the most prevalent serotype (55.2%) of penicillin-nonsusceptible isolates. Strain typing by repetitive element BOX polymerase chain reaction (PCR) analysis showed that penicillin-nonsusceptible serotype 14 isolates had closely related BOX PCR patterns, whereas penicillin-susceptible serotype 14 isolates each had distinct, unrelated patterns. Penicillin-nonsusceptible serotype 14 isolates from Salvador and other Brazilian cities had similar BOX PCR patterns. These observations indicate that in Brazil a large proportion of cases of penicillin-nonsusceptible pneumococcal meningitis appear to be caused by a closely related group of serotype 14 strains that may have disseminated to widely separate geographic areas. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | Cornell University Medical College. Division of International Medicine and Infectious Diseases. New York, New York | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | Secretaria de Saúde do Estado da Bahia. Hospital Couto Maia. Salvador, Bahia, Brasil | pt_BR |
Affilliation | Secretaria de Saúde do Estado da Bahia. Hospital Couto Maia. Salvador, BA, Brasil | pt_BR |
Affilliation | Universidade Federal da Bahia. Faculdade de Medicina. Salvador, BA, Brasil | pt_BR |
Affilliation | Universidade Federal da Bahia. Faculdade de Medicina. Salvador, BA, Brasil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | Cornell University Medical College. Division of International Medicine and Infectious Diseases. New York, New York | pt_BR |
Affilliation | University of California at Berkeley. Division of Public Health Biology and Epidemiology. Berkeley, CA, United States of America | pt_BR |
DeCS | Meningite Pneumocócica/epidemiologia | pt_BR |
DeCS | Meningite Pneumocócica/microbiologia | pt_BR |
DeCS | Resistência às Penicilinas | pt_BR |
DeCS | Streptococcus pneumoniae/classificação | pt_BR |
DeCS | Streptococcus pneumoniae/efeitos de drogas | pt_BR |
DeCS | Adolescente | pt_BR |
DeCS | Adulto | pt_BR |
DeCS | Antibacterianos/farmacologia | pt_BR |
DeCS | Brasil/epidemiologia | pt_BR |
DeCS | Criança | pt_BR |
DeCS | Pré-Escolar | pt_BR |
DeCS | Humanos | pt_BR |
DeCS | Lactente | pt_BR |
DeCS | Recém-Nascido | pt_BR |
DeCS | Testes de Sensibilidade Microbiana | pt_BR |
DeCS | Reação em Cadeia da Polimerase/métodos | pt_BR |
DeCS | Vigilância da População | pt_BR |
DeCS | Fatores de Risco | pt_BR |
DeCS | Sorotipagem | pt_BR |
DeCS | Streptococcus pneumoniae/genética | pt_BR |
DeCS | Streptococcus pneumoniae/isolamento & purificação | pt_BR |