Author | Carvalho, Janaína de Pina | |
Author | Assis, Tália Machado de | |
Author | Simões, Taynãna César | |
Author | Cota, Gláucia Fernandes | |
Access date | 2022-02-17T14:16:20Z | |
Available date | 2022-02-17T14:16:20Z | |
Document date | 2021 | |
Citation | CARVALHO, Janaína de Pina et al. Estimating direct costs of the treatment for mucosal leishmaniasis in Brazil. Rev Soc Bras Med Trop., v. 54, e04542020, 2021. doi: 10.1590/0037-8682-0454-2020. eCollection 2021. | pt_BR |
ISSN | 0037-8682 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/51269 | |
Language | eng | pt_BR |
Publisher | Sociedade Brasileira de Medicina Tropical | pt_BR |
Rights | open access | pt_BR |
Title | Estimating direct costs of the treatment for mucosal leishmaniasis in Brazil | pt_BR |
Type | Article | pt_BR |
Abstract | INTRODUCTION: The objective of this study was to estimate the direct medical costs of the treatment for mucosal leishmaniasis (ML) using three therapeutic approaches in the Brazilian context.
METHODS: We performed this economic assessment from the perspective of the Brazilian public healthcare system. The following therapeutic approaches were evaluated: meglumine antimoniate, liposomal amphotericin B, and miltefosine. Direct medical costs were estimated considering four treatment components: a) drug, b) combined medical products, c) procedures, and d) complementary tests.
RESULTS: Treatment with meglumine antimoniate had the lowest average cost per patient (US$ 167.66), followed by miltefosine (US$ 259.92) in the outpatient treatment regimen. The average cost of treatment with liposomal amphotericin B was US$ 715.35 both in inpatient regimen. In all estimates, the drugs accounted for more than 60% of the total cost for each treatment approach.
CONCLUSIONS: These results demonstrate the marked differences in costs between the therapeutic alternatives for ML. In addition to efficacy rates and costs related to adverse events, our data have the potential to support a complete cost-effectiveness study in the future. Complete analyses comparing costs and benefits for interventions will assist health managers in choosing drugs for ML treatment in Brazil as well as in establishing effective public health policies. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa Clínica e Políticas Públicas em Doenças Infecciosas e Parasitárias. Belo Horizonte, MG, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa Clínica e Políticas Públicas em Doenças Infecciosas e Parasitárias. Belo Horizonte, MG, Brasil./Centro Federal de Educação Tecnológica de Minas Gerais. Contagem, MG, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa Clínica e Políticas Públicas em Doenças Infecciosas e Parasitárias. Belo Horizonte, MG, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto René Rachou. Grupo de Pesquisa Clínica e Políticas Públicas em Doenças Infecciosas e Parasitárias. Belo Horizonte, MG, Brasil. | pt_BR |
Subject | Mucocutaneous leishmaniasis | pt_BR |
Subject | Cost analysis | pt_BR |
Subject | Drug therapy | pt_BR |
Subject | Meglumine antimoniate | pt_BR |
Subject | Liposomal amphotericin B | pt_BR |
Subject | Miltefosine | pt_BR |