Author | Paulino, Mariah Rodrigues | |
Author | Moreira, José Alfredo de Sousa | |
Author | Correia, Marcelo Goulart | |
Author | Santos, Léo Rodrigo Abrahão dos | |
Author | Duarte, Ingrid Paiva | |
Author | Sabioni, Letícia Roberto | |
Author | Mucillo, Fabiana Bergamin | |
Author | Garrido, Rafael Quaresma | |
Author | Pacheco, Stephan Lachtermacher | |
Author | Lorenzo, Andrea de | |
Author | Lamas, Cristiane da Cruz | |
Access date | 2022-01-24T13:55:06Z | |
Available date | 2022-01-24T13:55:06Z | |
Document date | 2021 | |
Citation | PAULINO, Mariah Rodrigues et al. COVID-19 in patients with cardiac disease: Impact and variables associated with mortality in a cardiology center in Brazil. American Heart Journal Plus, v. 12, 100069, p. 1-7, 2021. | pt_BR |
ISSN | 2666-6022 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/50857 | |
Description | Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. | pt_BR |
Language | eng | pt_BR |
Publisher | Elsevier | pt_BR |
Rights | open access | pt_BR |
Title | COVID-19 in patients with cardiac disease: Impact and variables associated with mortality in a cardiology center in Brazil | pt_BR |
Type | Article | pt_BR |
DOI | 10.1016/j.ahjo.2021.100069 | |
Abstract | Background: Cardiovascular disease is associated with severe COVID-19. Our aim was to describe clinical and laboratory features (including electrocardiographic and echocardiographic ones) and outcomes of patients with cardiac disease hospitalized with COVID-19.
Methods: This is an observational retrospective study of consecutive adult patients admitted, between March and September of 2020, with confirmed SARSCoV-2 infection. Data were collected as per the ISARIC case report form and complemented with variables related to heart disease.
Results: One hundred twenty-one patients were included. Mean age was 60 SD 15.2 years and 80/121(66.1%) were male. Two-thirds of the patients (80/121, 66.1%) had COVID-19 at the time of hospital admission and COVID-19 was the reason for hospitalization in 42 (34.7%). Other reasons for hospital admission were acute coronary syndrome (26%) and decompensated heart failure (14.8%). Chronic cardiac diseases were found in 106/121 (87.6%), mostly coronary artery disease (62%) or valve disease (33.9%). A transthoracic echocardiogram was performed in 93/121(76.8%) and enlarged cardiac chambers were found in 71% (66/93); admission ECG was done in 93 cases (93/121, 76.8%), and 89.2% (83/93) were abnormal. Hospital-acquisition of COVID-19 occurred in 20 (16.5%) of patients and their mortality was 50%. On bivariate analysis for mortality, BNP levels and troponin levels were NOT associated with mortality. On multivariate analysis, only C reactive protein levels and creatinine levels were significant.
Conclusions: COVID-19 impacted the profile of hospital admissions in cardiac patients. BNP and troponin levels were not associated with mortality and may not be good prognostic discriminators in cardiac patients. | pt_BR |
Affilliation | Instituto Nacional de Cardiologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Instituto Nacional de Cardiologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Instituto Nacional de Cardiologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade do Grande Rio. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade do Grande Rio. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Instituto Nacional de Cardiologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Instituto Nacional de Cardiologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Instituto Nacional de Cardiologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Instituto Nacional de Cardiologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Instituto Nacional de Cardiologia. Rio de Janeiro, RJ, Brasil / Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil / Instituto Nacional de Cardiologia. Rio de Janeiro, RJ, Brasil / Universidade do Grande Rio, Rio de Janeiro, RJ, Brasil. | pt_BR |
Subject | COVID-19 | pt_BR |
Subject | Cardiac disease | pt_BR |
Subject | Cardiac surgery | pt_BR |
Subject | Coronavirus | pt_BR |
Subject | Hospitalization | pt_BR |
Subject | Mortality | pt_BR |