Author | Almeida, Nathália Alves Araújo de | |
Author | Ribeiro, Camilla Rodrigues de Almeida | |
Author | Raposo, Jéssica Vasques | |
Author | Paula, Vanessa Salete de | |
Access date | 2021-09-17T10:58:22Z | |
Available date | 2021-09-17T10:58:22Z | |
Document date | 2021 | |
Citation | ALMEIDA, Nathália Alves Araújo de et al. Immunotherapy and Gene Therapy for Oncoviruses Infections: A Review. Viruses, v. 13, n. 822, 18 p, May 2021. | pt_BR |
ISSN | 1999-4915 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/49100 | |
Language | eng | pt_BR |
Publisher | MDPI | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | Imunoterapia | pt_BR |
Subject in Portuguese | Terapia genética e oncovírus | pt_BR |
Title | Immunotherapy and Gene Therapy for Oncoviruses Infections: A Review | pt_BR |
Type | Article | pt_BR |
DOI | 10.3390/v13050822 | |
Abstract | Immunotherapy has been shown to be highly effective in some types of cancer caused
by viruses. Gene therapy involves insertion or modification of a therapeutic gene, to correct for
inappropriate gene products that cause/may cause diseases. Both these types of therapy have been
used as alternative ways to avoid cancers caused by oncoviruses. In this review, we summarize
recent studies on immunotherapy and gene therapy including the topics of oncolytic immunotherapy,
immune checkpoint inhibitors, gene replacement, antisense oligonucleotides, RNA interference,
clustered regularly interspaced short palindromic repeats Clustered Regularly Interspaced Short
Palindromic Repeats (CRISPR)-based gene editing, transcription activator-like effector nucleases
(TALENs) and custom treatment for Epstein–Barr virus, human T-lymphotropic virus 1, hepatitis
B virus, human papillomavirus, hepatitis C virus, herpesvirus associated with Kaposi’s sarcoma,
Merkel cell polyomavirus, and cytomegalovirus. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Virologia Molecular. Rio de Janeiro, RJ, Brasil. | pt_BR |
Subject | Immunotherapy | pt_BR |
Subject | Gene therapy and oncovirus | pt_BR |