Author | Vigoder, Felipe M. | |
Author | Araripe, Luciana O. | |
Author | Carvalho, Antonio Bernardo | |
Access date | 2021-07-12T13:33:03Z | |
Available date | 2021-07-12T13:33:03Z | |
Document date | 2021 | |
Citation | VIGODER, Felipe M.; ARARIPE, Luciana O.; CARVALHO, Antonio Bernardo. Identification of the sex chromosome system in a sand fly species, Lutzomyia longipalpis s.l. G3, jkab217, 7 p, June 2021. . | pt_BR |
ISSN | 2160-1836 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/48142 | |
Language | eng | pt_BR |
Publisher | Oxford University Press | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | Moscas de areia | pt_BR |
Subject in Portuguese | Sistema de cromossomo sexual | pt_BR |
Subject in Portuguese | Lutzomyia longipalpis | pt_BR |
Subject in Portuguese | Genética do Sexo | pt_BR |
Subject in Portuguese | Psychodidae | pt_BR |
Subject in Portuguese | Diptera | pt_BR |
Subject in Portuguese | Cromossomo Y | pt_BR |
Title | Identification of the sex chromosome system in a sand fly species, Lutzomyia longipalpis s.l. | pt_BR |
Type | Article | pt_BR |
DOI | 10.1093/g3journal/jkab217 | |
Abstract | In many animal species, sex determination is accomplished by heterogamety i.e., one of the sexes produces two types of gametes, which
upon fertilization will direct the development toward males or females. Both male (“XY”) and female (“ZW”) heterogamety are known to
occur and can be easily distinguished when the sex-chromosomes are morphologically different. However, this approach fails in cases of
homomorphic sex chromosomes, such as the sand fly Lutzomyia longipalpis s.l. (Psychodidae, Diptera), which is the main vector of visceral
leishmaniosis in Brazil. In order to identify the heterogametic sex in L. longipalpis s.l., we did a whole-genome sequencing of males and
females separately and used the “Y chromosome Genome Scan” (YGS) method to find sex-specific sequences. Our results, which were
confirmed by PCR, show that L. longipalpis s.l. has XY system. The YGS method can be especially useful in situations in which no morpho logical difference is observed in the sex-chromosomes or when fresh specimens are not readily available. | pt_BR |
Affilliation | Universidade Federal do Rio de Janeiro. CCS. Instituto de Biologia. Departamento de Genética. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Biologia Molecular de Insetos. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade Federal do Rio de Janeiro. CCS. Instituto de Biologia. Departamento de Genética. Rio de Janeiro, RJ, Brasil. | pt_BR |
Subject | Sand flies | pt_BR |
Subject | Sex chromosome system | pt_BR |
Subject | Y chromosome | pt_BR |
Subject | YGS | pt_BR |
Subject | Lutzomyia longipalpis | pt_BR |
Subject | Psychodidae | pt_BR |
Subject | Diptera | pt_BR |
Subject | Genetics of Sex | pt_BR |