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https://www.arca.fiocruz.br/handle/icict/47310
CRYPTORCHIDISM IN CHILDREN WITH ZIKA-RELATED MICROCEPHALY
Child Preschool
Cryptorchidism
Humans
Infant
Infant Newborn
Male
Microcephaly
Rick Factors
Zika Virus Infection
Pré-Escolar
Criptorquidismo
Humanos
Lactente
Recém-Nascido
Masculino
Microcefalia
Fatores de Risco
Infecção por Zika virus
Author
Affilliation
Universidade de Pernambuco. Recife, PE, Brazil.
Universidade de Pernambuco. Recife, PE, Brazil.
Universidade de Pernambuco. Recife, PE, Brazil.
Fundação Oswaldo Cruz. Instituto de Pesquisa Aggeu Magalhães. Recife, PE, Brazil.
Universidade Federal de Pernambuco. Recife, PE, Brazil.
London School of Hygiene and Tropical Medicine. London, United Kingdom.
Universidade Federal de Pernambuco. Recife, PE, Brazil.
Universidade Federal de Pernambuco. Recife, PE, Brazil.
Universidade de Pernambuco. Recife, PE, Brazil.
Universidade de Pernambuco. Recife, PE, Brazil.
Fundação Oswaldo Cruz. Instituto de Pesquisa Aggeu Magalhães. Recife, PE, Brazil.
Universidade Federal de Pernambuco. Recife, PE, Brazil.
London School of Hygiene and Tropical Medicine. London, United Kingdom.
Universidade Federal de Pernambuco. Recife, PE, Brazil.
Universidade Federal de Pernambuco. Recife, PE, Brazil.
Abstract
The genitourinary tract was recently identified as a potential site of complications related to the congenital Zika syndrome (CZS). We provide the first report of a series of cryptorchidism cases in 3-year-old children with Zikarelated microcephaly who underwent consultations between October 2018 and April 2019 as part of the follow-up of the children cohort of the Microcephaly Epidemic Research Group, Pernambuco, Brazil. Of the 22 males examined, eight (36.4%) presented with cryptorchidism. Among 14 undescended testis cases, 11 (78.6%) could be palpated in the inguinal region. Seven of the eight children had severe microcephaly. Conventional risk factors for cryptorchidism were relatively infrequent in these children.Wehypothesize that cryptorchidism is an additional manifestation ofCZSpresent in children with severe microcephaly. As in our cases, for most of the children, the testes were located in the inguinal region, and the possible mechanisms for cryptorchidism were gubernaculum disturbance or cremasteric abnormality.
Keywords
BrazilChild Preschool
Cryptorchidism
Humans
Infant
Infant Newborn
Male
Microcephaly
Rick Factors
Zika Virus Infection
DeCS
BrasilPré-Escolar
Criptorquidismo
Humanos
Lactente
Recém-Nascido
Masculino
Microcefalia
Fatores de Risco
Infecção por Zika virus
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