Author | Smeaton, Laura M. | |
Author | Kileel, Emma M. | |
Author | Grinsztejn, Beatriz | |
Author | Gardner, Edward M. | |
Author | Starr, Kate | |
Author | Murry, Melissa L. | |
Author | Desvigne-Nickens, Patrice | |
Author | Alston-Smith, Beverly | |
Author | Waclawiw, Myron A. | |
Author | Cooper-Arnold, Katharine | |
Author | Madruga, José V. | |
Author | Sangle, Shashi | |
Author | Fitch, Kathleen V. | |
Author | Zanni, Markella V. | |
Author | Douglas, Pamela S. | |
Author | Ribaudo, Heather J. | |
Author | Grinspoon, Steven K. | |
Author | Klingman, Karin L. | |
Access date | 2020-08-31T23:16:21Z | |
Available date | 2020-08-31T23:16:21Z | |
Document date | 2020 | |
Citation | SMEATON, Laura M et al. Characteristics of REPRIEVE Trial Participants Identifying Across the Transgender Spectrum. The Journal of Infectious Diseases, v. 222, n. 1, p. 31-40, 2020. | pt_BR |
ISSN | 0022-1899 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/43098 | |
Language | eng | pt_BR |
Publisher | Oxford | pt_BR |
Rights | open access | pt_BR |
Title | Characteristics of REPRIEVE Trial Participants Identifying Across the Transgender Spectrum | pt_BR |
Type | Article | pt_BR |
DOI | 10.1093/infdis/jiaa213 | |
Abstract | Because persons who identify across the transgender spectrum (PATS) are a key population in human immunodeficiency virus (HIV) yet are underreported in HIV and cardiovascular research, we aimed to characterize this population within the REPRIEVE global clinical trial (n = 7770). Acceptance of gathering gender identity was high (96%). Participation by PATS was 1.7% overall, 2.4% among natal males, 0.3% among natal females, and varied across geographic regions (from 0% in sub-Saharan Africa to 2.3% in High Income Region). Thirty percent of natal male PATS identified other than transgender. Some characteristics differed by gender. Most notably, 38% of natal male PATS receiving gender-affirming treatment had waist circumference >102 cm (compared with ≤25% in other groups). Given that PATS is a key population, HIV research should routinely report trial participation and outcomes by gender in addition to natal sex, to provide the results needed to optimize medical care to PATS. | pt_BR |
Affilliation | Harvard T. H. Chan School of Public Health. Center for Biostatistics in AIDS Research. Boston, Massachusetts, USA. | pt_BR |
Affilliation | Massachusetts General Hospital and Harvard Medical School. Metabolism Unit. Boston, Massachusetts, USA. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Denver Public Health. Denver, Colorado, USA. | pt_BR |
Affilliation | The Ohio State University. Columbus, Ohio, USA. | pt_BR |
Affilliation | Houston Cross Network Community Advisory Board. Houston, Texas, USA. | pt_BR |
Affilliation | National Institutes of Health. National Heart, Lung, and Blood Institute. Bethesda, Maryland, USA. | pt_BR |
Affilliation | National Institutes of Health. National Institute of Allergy and Infectious Diseases. Bethesda, Maryland, USA. | pt_BR |
Affilliation | National Institutes of Health. National Heart, Lung, and Blood Institute. Bethesda, Maryland, USA. | pt_BR |
Affilliation | National Institutes of Health. National Heart, Lung, and Blood Institute. Bethesda, Maryland, USA. | pt_BR |
Affilliation | Centro de Referencia e Treinamento DST/AIDS. São Paulo, SP, Brasil. | pt_BR |
Affilliation | BJ Medical College. Department of Medicine. Pune, India. | pt_BR |
Affilliation | Massachusetts General Hospital and Harvard Medical School. Metabolism Unit. Boston, Massachusetts, USA. | pt_BR |
Affilliation | Massachusetts General Hospital and Harvard Medical School. Metabolism Unit. Boston, Massachusetts, USA. | pt_BR |
Affilliation | Duke University School of Medicine. Duke Clinical Research Institute. Durham, North Carolina, USA. | pt_BR |
Affilliation | Harvard T. H. Chan School of Public Health. Center for Biostatistics in AIDS Research. Boston, Massachusetts, USA. | pt_BR |
Affilliation | Massachusetts General Hospital and Harvard Medical School. Metabolism Unit. Boston, Massachusetts, USA. | pt_BR |
Affilliation | National Institutes of Health. National Institute of Allergy and Infectious Diseases. Bethesda, Maryland, USA. | pt_BR |
Subject | HIV | pt_BR |
Subject | Cardiovascular | pt_BR |
Subject | Gender identity | pt_BR |
Subject | Gender-affirming hormone treatment | pt_BR |
Subject | Transgender spectrum | pt_BR |