Author | Fernandes, Andréia da Silva | |
Author | Alencar, Alexandre Santos | |
Author | Evangelista, Heitor | |
Author | Mazzei, José Luiz | |
Author | Felzenszwalb, Israel | |
Access date | 2020-03-17T13:52:14Z | |
Available date | 2020-03-17T13:52:14Z | |
Document date | 2015 | |
Citation | FERNANDES, Andréia da Silva et al. Photoprotective and toxicological activities of extracts from the Antarctic moss Sanionia uncinata. Pharmacognosy Magazine, v. 11, n. 41, 2015. | pt_BR |
ISSN | 0973-1296 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/40352 | |
Language | eng | pt_BR |
Rights | open access | pt_BR |
Title | Photoprotective and toxicological activities of extracts from the Antarctic moss Sanionia uncinata | pt_BR |
Type | Article | pt_BR |
Abstract | The Antarctic moss Sanionia uncinata (Hedw.) Loeske has shown high
ultraviolet (UV)‑absorbers content after exposition to high levels of UV‑B radiation and can be
an important source of antioxidants. Objective: The aim was to investigate photoprotection and
mutagenicity by the aqueous extract (AE) and hydroethanolic extract (HE) from the Antarctic
moss S. uncinata. Materials and Methods: Photoprotective activities were determined through
survival curves of Escherichia coli strains, after UV irradiation in an aqueous solution of thymine
and in vitro sun protection factor (SPF). The Salmonella/microsome assays were applied to assess
the mutagenicity. Results: Both extracts induced photoprotection against UV‑C radiation. The AE
showed a higher protection than the hydroethanolic one against UV‑induced thymine dimerization.
The SPFs were low in both extracts. In association to benzophenone‑3 a significant increase
in the SPF was detected for the AE, and a significant decrease was induced by the HE. No
mutagenicity was found in the both extracts. Furthermore, it was observed absence of cytotoxicity.
Conclusion: Water‑extractable compounds seem to contribute on photoprotection of this Antarctic moss. | pt_BR |
Affilliation | Universidade do Estado do Rio de Janeiro. Instituto de Biologia Roberto Alcântara Gomes. Departamento de Biofísica e Biometria. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade do Estado do Rio de Janeiro. Instituto de Biologia Roberto Alcântara Gomes. Departamento de Biofísica e Biometria. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade do Estado do Rio de Janeiro. Instituto de Biologia Roberto Alcântara Gomes. Departamento de Biofísica e Biometria. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto de Tecnologia em Fármacos. Plataforma de Análise Química. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade do Estado do Rio de Janeiro. Instituto de Biologia Roberto Alcântara Gomes. Departamento de Biofísica e Biometria. Rio de Janeiro, RJ, Brasil. | pt_BR |
Subject | Moss | pt_BR |
Subject | Mutagenicity | pt_BR |
Subject | Photoprotection | pt_BR |
Subject | Sun Protection Factor | pt_BR |
Subject | Thymine‑Dimer Inhibition | pt_BR |
e-ISSN | 10.4103/0973-1296.149701 | |