Author | Nogueira, R. M. R. | |
Author | Filippis, A. M. B. | |
Author | Coelho, J. M. O. | |
Author | Sequeira, P. C. | |
Author | Schatzmayr, H. G. | |
Author | Paiva, F. G. | |
Author | Ramos, A. M. O. | |
Author | Miagostovich, M. P. | |
Access date | 2020-01-10T15:32:49Z | |
Available date | 2020-01-10T15:32:49Z | |
Document date | 2002 | |
Citation | NOGUEIRA, R. M. R. et al. Dengue virus infection of the central nervous system (CNS): a case report from Brazil. Southeast Asian Journal of Tropical Medicine and Public Health, v. 33, n. 1, p. 68-71, Mar. 2002. | pt_BR |
ISSN | 0125-1562 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/39140 | |
Language | eng | en |
Publisher | SEAMEO Regional Tropical Medicine and Public Health Network | pt_BR |
Rights | open access | pt_BR |
Title | Dengue virus infection of the central nervous system (CNS): a case report from Brazil | pt_BR |
Type | Article | pt_BR |
Abstract | Dengue infection that is accompanied by unusual complications has been described in Brazil. We report on the presence of dengue virus in the central nervous system (CNS) of a patient who died in 1998 in Rio Grande do Norte, northeast Brazil. DEN-2 viruses were isolated from the brain liver, and lymphnode tissue of a 67-year-old man whose signs and symptoms were those of dengue infection and a secondary immune response. A postmortem revealed nose bleeds a liver that was brownish with yellow areas, and pulmonary and cerebrae congestion. Immunoperoxidase staining showed a dengue antigen-specific positive reaction in the gray matter cells of the cerebrall cortex; a granular citoplasmatic reaction was seen in the neurons. Dengue infection should always be considered as a cause encephalitis in tropical countries, especially in those where the disease is endemic. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Laboratório Central de Saúde Pública do Rio Grande do Norte. Natal, RN, Brasil | pt_BR |
Affilliation | Setor de Verificação de Óbitos. Natal, RN, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Departamento de Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
Subject | Dengue | pt_BR |
Subject | Central nervous system | pt_BR |
Subject | Brazil | pt_BR |