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ZIKA VIRUS INFECTION - AFTER THE PANDEMIC
Infecção pelo vírus Zika
Pandemias
Microcefalia
Complicações Infecciosas na Gravidez
Gravidez
Zika virus infection
Pandemics
Microcephaly
Pregnancy Complications, Infectious
Pregnancy
Affilliation
Aix Marseille Université. Institut de Recherche pour le Développement. Hôpitaux de Marseille. Service de Santé des Armées. Vecteurs–Infections Tropicales et Méditerranéennes. Marseille, France / Institut Hospitalo-Universitaire Méditerranée Infection. Marseille,
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.
Centre Hospitalier Universitaire Vaudois. Materno-foetal and Obstetrics Research Unit. Department Femme-Mère-Enfant. Lausanne, Switzerland / University of Lausanne. Faculty of Biology and Medicine. Lausanne. Switzerland.
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.
Centre Hospitalier Universitaire Vaudois. Materno-foetal and Obstetrics Research Unit. Department Femme-Mère-Enfant. Lausanne, Switzerland / University of Lausanne. Faculty of Biology and Medicine. Lausanne. Switzerland.
Abstract
Zika virus (ZIKV) was discovered in Africa in 1947 and was first detected
in Asia in 1966, yet its potential effect on public health was not recognized
until the virus caused outbreaks in the Pacific from 2007 to 2015
and began spreading throughout the Americas in 2015.1,2 The ability of ZIKV to
cause congenital defects in fetuses and infants, as exemplified by the microcephaly
epidemic in Brazil, is an unprecedented feature in a mosquito-borne viral infection.
2-4 Although transmission of ZIKV has declined in the Americas, outbreaks
and infection clusters continue to occur in some regions, such as India and Southeast
Asia, where there are large populations of women of childbearing age who
are susceptible to the virus.5 We review the body of information that was acquired
during the pandemic and discuss the epidemiologic trends, current knowledge
about the transmission and natural history of ZIKV infection and its sequelae, and
the principles of diagnosis and clinical management.
Keywords in Portuguese
Virus ZikaInfecção pelo vírus Zika
Pandemias
Microcefalia
Complicações Infecciosas na Gravidez
Gravidez
Keywords
Zika virusZika virus infection
Pandemics
Microcephaly
Pregnancy Complications, Infectious
Pregnancy
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