Author | Rodrigues, Rosana Souza | |
Author | Marchiori, Edson | |
Author | Bozza, Fernando A. | |
Author | Pitrowsky, Melissa Tassano | |
Author | Velasco, Eduardo | |
Author | Soares, Márcio | |
Author | Salluh, Jorge I. F. | |
Access date | 2019-10-16T11:34:47Z | |
Available date | 2019-10-16T11:34:47Z | |
Document date | 2012 | |
Citation | RODRIGUES, Rosana Souza et al. Chest computed tomography findings in severe influenza pneumonia occurring in neutropenic cancer patients. Clinics, v. 67, n. 4, p. 313-318, 2012. | pt_BR |
ISSN | 1807-5932 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/36478 | |
Language | eng | pt_BR |
Publisher | Faculdade de Medicina / USP | pt_BR |
Rights | open access | pt_BR |
Title | Chest computed tomography findings in severe influenza pneumonia occurring in neutropenic cancer patients | pt_BR |
Type | Article | pt_BR |
DOI | 10.6061/clinics/2012(04)03 | |
Abstract | OBJECTIVE: To describe the chest computed tomography findings for severe influenza H1N1 infection in a series of hospitalized neutropenic cancer patients. METHODS: We performed a retrospective systematic analysis of chest computed tomography scans for eight hospitalized patients with fever, neutropenia, and confirmed diagnoses of influenza H1N1. The clinical data had been prospectively collected. RESULTS: Six of eight patients (75%) developed respiratory failure and required intensive care. Prolonged H1N1 shedding was observed in the three mechanically ventilated patients, and overall hospital mortality in our series was 25%. The most frequent computed tomography findings were ground-glass opacity (all patients), consolidation (7/8
cases), and airspace nodules (6/8 cases) that were frequently moderate or severe. Other parenchymal findings were not common. Five patients had features of pneumonia, two had computed tomography findings compatible with bronchitis and/or bronchiolitis, and one had tomographic signs of chronicity. CONCLUSION: In this series of neutropenic patients with severe influenza H1N1 infection, chest computed tomography demonstrated mainly moderate or severe parenchymatous disease, but bronchiolitis was not a common feature. These findings associated with febrile neutropenia should elicit a diagnosis of severe viral infection. | pt_BR |
Affilliation | Federal University of Rio de Janeiro. Rio de Janeiro, RJ, Brazil / D’Or Institute for Research and Education. Rio de Janeiro, RJ, Brazil. | pt_BR |
Affilliation | Federal University of Rio de Janeiro. Rio de Janeiro, RJ, Brazil. | pt_BR |
Affilliation | D’Or Institute for Research and Education. Rio de Janeiro, RJ, Brazil / Fundação Oswaldo Cruz. Instituto de Pesquisa Clínica Evandro Chagas. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Instituto Nacional de Câncer. Intensive Care Unit and Postgraduate Program. Rio de Janeiro, RJ, Brazil. | pt_BR |
Affilliation | Instituto Nacional de Câncer. Infectious Diseases Department. Rio de Janeiro, RJ, Brazil. | pt_BR |
Affilliation | D’Or Institute for Research and Education. Rio de Janeiro, RJ, Brazil / Instituto Nacional de Câncer. Intensive Care Unit and Postgraduate Program. Rio de Janeiro, RJ, Brazil. | pt_BR |
Affilliation | D’Or Institute for Research and Education. Rio de Janeiro, RJ, Brazil / Instituto Nacional de Câncer. Intensive Care Unit and Postgraduate Program. Rio de Janeiro, RJ, Brazil. | pt_BR |
Subject | H1N1 | pt_BR |
Subject | Viral pneumonia | pt_BR |
Subject | Neutropenia | pt_BR |
Subject | Cancer | pt_BR |
Subject | Computed tomography | pt_BR |
e-ISSN | 1980-5322 | |