Author | Villar, Livia Melo | |
Author | Geloneze, Bruno | |
Author | Vasques, Ana Carolina Junqueira | |
Author | Pires, Maria Lucia Elias | |
Author | Miguel, Juliana Custódio | |
Author | Silva, Elisangela Ferreira da | |
Author | Marques, Vanessa Alves | |
Author | Scalioni, Leticia de Paula | |
Author | Lampe, Elisabeth | |
Access date | 2019-08-29T12:06:25Z | |
Available date | 2019-08-29T12:06:25Z | |
Document date | 2019 | |
Citation | VILLAR, Livia Melo et al. Prevalence of hepatitis B and hepatitis C among diabetes mellitus type 2 individuals. Plos One, v. 14, n. 2, p. 1-10, Feb. 2019. | pt_BR |
ISSN | 1932-6203 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/35178 | |
Language | eng | pt_BR |
Publisher | Public Library of Science | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | Hepatite B | pt_BR |
Subject in Portuguese | Hepatite C | pt_BR |
Subject in Portuguese | Diabetes mellitus tipo 2 | pt_BR |
Subject in Portuguese | Prevalência | pt_BR |
Title | Prevalence of hepatitis B and hepatitis C among diabetes mellitus type 2 individuals | pt_BR |
Type | Article | pt_BR |
DOI | 10.1371/journal.pone.0211193 | |
Abstract | Diabetes mellitus type 2 (DM2) patients have higher risk to be infected with parenterally transmitted viruses, like hepatitis B or C virus. This study aims to determine HBV and HCV infection prevalence in DM2 patients from Northeast and Southeast Brazil. A total of 537 DM2 patients were included, 194 (36.12%) males and 343 (63.87%) females, with mean age of 57.13±11.49 years. HBV and HCV markers were determined using serological and molecular analysis, and risk factors were evaluated in a subgroup from Southeast (n = 84). Two HBV acute (HBsAg+/anti-HBc -) and one HBV chronic case (HBsAg+/anti-HBc+) were found. Six individuals (1.1%) were isolated anti-HBc, 37 (6.9%) had HBV infection resolved (anti-HBc+/anti-HBs+), 40 (7.4%) were considered HBV vaccinated (anti-HBc-/anti-HBs+). Thirteen patients (2.42%) had anti-HCV and 7 of them were HCV RNA+. In the subgroup, anti-HBc positivity was associated to age and anti-HCV positivity was associated to age, time of diabetes diagnosis, total bilirubin, indirect bilirubin, alkaline phosphatase at bivariate analysis, but none of them was statistically significant at multivariate analysis. As conclusion, low prevalence of HBV and high prevalence HCV was found in DM2 patients. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade de Campinas. Gastrocentro. Laboratório de Investigação em Metabolismo e Diabetes. Campinas, SP, Brasil. | pt_BR |
Affilliation | Universidade de Campinas. Gastrocentro. Laboratório de Investigação em Metabolismo e Diabetes. Campinas, SP, Brasil / Universidade de Campinas. Escola de Ciências Aplicadas. Campinas, SP, Brasil. | pt_BR |
Affilliation | Universidade Federal do Estado do Rio de Janeiro. Escola de Medicina. Departamento de Medicina Clínica de Cirurgia. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Hepatites Virais. Rio de Janeiro, RJ, Brasil. | pt_BR |
Subject | Hepatitis B | pt_BR |
Subject | Hepatitis C | pt_BR |
Subject | Diabetes Millitus type 2 | pt_BR |
Subject | Prevalence | pt_BR |