Please use this identifier to cite or link to this item:
https://www.arca.fiocruz.br/handle/icict/34730
Type
ArticleCopyright
Restricted access
Embargo date
2022-01-01
Collections
Metadata
Show full item record
AN OVERVIEW ON LEISHMANIA (MUNDINIA) ENRIETTII: BIOLOGY, IMMUNOPATHOLOGY, LRV AND EXTRACELLULAR VESICLES DURING THE HOST-PARASITE INTERACTION
Extracellular vesicles
Glycobiology
Immunopathology
Innate immunity
L. (Mundinia) subgenus
Leishmania (Mundinia) enriettii
RNA virus
Author
Affilliation
Universidade Federal de Minas Gerais. Departamento de Parasitologia. Belo Horizonte, MG, Brasil.
Universidade Federal de Minas Gerais. Departamento de Patologia Geral. Belo Horizonte, MG, Brasil.
Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil.
Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil.
Universidade Federal de São Paulo. Departamento de Farmácia. Diadema, SP, Brasil.
Universidade Federal de Minas Gerais. Departamento de Patologia Geral. Belo Horizonte, MG, Brasil.
Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil.
Universidade Federal de Minas Gerais. Departamento de Patologia Geral. Belo Horizonte, MG, Brasil.
Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil.
Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil.
Universidade Federal de São Paulo. Departamento de Farmácia. Diadema, SP, Brasil.
Universidade Federal de Minas Gerais. Departamento de Patologia Geral. Belo Horizonte, MG, Brasil.
Fundação Oswaldo Cruz. Instituto René Rachou. Belo Horizonte, MG, Brasil.
Abstract
One of the Leishmania species known to be non-infective to humans is Leishmania (Mundinia) enriettii whose vertebrate host is the guinea pig Cavia porcellus. It is a good model for cutaneous leishmaniasis, chemotherapeutic and molecular studies. In the last years, an increased interest has emerged concerning the L. (Mundinia) subgenus after the finding of Leishmania (M.) macropodum in Australia and with the description of other new/putative species such as L. (M.) martiniquensis and 'L. (M.) siamensis'. This review focused on histopathology, glycoconjugates and innate immunity. The presence of Leishmania RNA virus and shedding of extracellular vesicles by the parasite were also evaluated.
Keywords
ChemotherapyExtracellular vesicles
Glycobiology
Immunopathology
Innate immunity
L. (Mundinia) subgenus
Leishmania (Mundinia) enriettii
RNA virus
Share