Author | Fernandes, Flavia F. | |
Author | Piedade, Juliana | |
Author | Guimaraes, Livia | |
Author | Nunes, Estevao P. | |
Author | Chaves, Ursula B. | |
Author | Goldenzon, Rafaela V. | |
Author | Cardoso, Sandra W. | |
Author | Duarte, Joana | |
Author | Grinsztejn, Beatriz | |
Author | Veloso, Valdiléa G. | |
Author | Pereira, Gustavo | |
Author | Perazzo, Hugo | |
Access date | 2019-06-13T12:06:38Z | |
Available date | 2019-06-13T12:06:38Z | |
Document date | 2019 | |
Citation | FERNANDES, Flavia F. et al. Effectiveness of direct-acting agents for hepatitis C and liver stiffness changing after sustained virological response. Journal of Gastroenterology and Hepatology, p. 1-24, May 2019. | pt_BR |
ISSN | 0815-9319 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/33484 | |
Language | eng | pt_BR |
Publisher | Wiley | pt_BR |
Rights | open access | pt_BR |
Title | Effectiveness of direct-acting agents for hepatitis C and liver stiffness changing after sustained virological response | pt_BR |
Type | Article | pt_BR |
DOI | 10.1111/jgh.14707 | |
Abstract | Few studies have evaluated sustained virological response (SVR) rates by direct antivirals (DAAs) and liver stiffness measurement (LSM) changing post-SVR in limited-resource settings. We aimed to describe the effectiveness of DAAs for HCV treatment and to assess the changing of LSM post-SVR METHODS: This retrospective study analyzed data of consecutive HCV-infected patients treated by DAAs from 2015 to 2017 in two tertiary centers in Brazil. SVR rates were reported by intention-to-treat (ITT) and per-protocol analysis. LSM by transient elastography performed before treatment and post-SVR were compared and logistic regression models were performed. | pt_BR |
Affilliation | Bonsucesso Federal Hospital. Gastroenterology Department. Rio de Janeiro, RJ, Brazil. | pt_BR |
Affilliation | Bonsucesso Federal Hospital. Gastroenterology Department. Rio de Janeiro, RJ, Brazil / Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST e AIDS. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Bonsucesso Federal Hospital. Gastroenterology Department. Rio de Janeiro, RJ, Brazil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST e AIDS. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST e AIDS. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST e AIDS. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST e AIDS. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Bonsucesso Federal Hospital. Gastroenterology Department. Rio de Janeiro, RJ, Brazil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST e AIDS. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST e AIDS. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Bonsucesso Federal Hospital. Gastroenterology Department. Rio de Janeiro, RJ, Brazil / Estácio de Sá University. Rio de Janeiro, RJ, Brazil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST e AIDS. Rio de Janeiro, RJ, Brasil. | pt_BR |
Subject | Hepatitis C | pt_BR |
Subject | Liver stiffness | pt_BR |
Subject | Virological response | pt_BR |
e-ISSN | 1440-1746 | |
Embargo date | 2020-06-13 | |