Author | Vitral, C. L. | |
Author | Souto, F. J. D. | |
Author | Gaspar, A. M. C. | |
Access date | 2019-03-28T15:41:20Z | |
Available date | 2019-03-28T15:41:20Z | |
Document date | 2008 | |
Citation | VITRAL, C. L.; SOUTO, F. J. D.; GASPAR, A. M. C. Changing epidemiology of hepatitis A in Brazil: reassessing immunization policy. Journal of Viral Hepatitis, v. 15, Suppl. 2, p. 22-25, 2008. | pt_BR |
ISSN | 1352-0504 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/32272 | |
Language | eng | pt_BR |
Publisher | Wiley 12 Months | pt_BR |
Rights | restricted access | pt_BR |
Subject in Portuguese | Hepatite A | pt_BR |
Subject in Portuguese | Vírus da Hepatite A | pt_BR |
Subject in Portuguese | Epidemiologia | pt_BR |
Subject in Portuguese | Brasil | pt_BR |
Title | Changing epidemiology of hepatitis A in Brazil: reassessing immunization policy | pt_BR |
Type | Article | pt_BR |
Abstract | Recent studies have shown that the prevalence
of antibody to hepatitis A virus (HAV) is decreasing in
several Latin American countries. Brazil is a very large
and heterogeneous country, showing striking regional
differences. With regard to sanitary facilities, 81.7% of the
districts in the south-eastern region have sewage systems,
compared with only 5.8% in the northern region. Results
of sero-epidemiological studies and reported hepatitis A
outbreaks indicate a change in the epidemiological pattern
of hepatitis A in the country. Individuals, especially those
under the age of 10, are mostly unprotected from HAV
infection, regardless of their socioeconomic status. During
2000–2005, approximately 14 000–21 000 cases of hepatitis
A were reported annually in Brazil, a rate of 7.5–11
cases per 100 000 population. Nationwide, hepatitis A
mortality rates declined progressively from 1980 to 2002.
As fatal cases constitute a small, but predictable, portion
of all acute hepatitis A cases, which are in turn part of
the total number of HAV infections, these data suggest
that there has been a decline in HAV circulation in all
Brazilian regions over the last two decades. Taken together
these facts point out that the epidemiological pattern of
hepatitis A is changing in Brazil. Besides improvements in
sanitary conditions in the poorest Brazilian regions, the
introduction of hepatitis A vaccination of young children
could be a strategy for controlling HAV infection in the
country. | pt_BR |
Affilliation | Universidade Federal Fluminense. Instituto de Biologia. Departamento de Microbiologia e Parasitologia. Niterói, RJ, Brasil / Fundação Oswaldo Cruz. Laboratório de Desenvolvimento Tecnológico. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade Federal de Mato Grosso. Faculdade de Ciências Médicas. Cuiabá, MT, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Laboratório de Desenvolvimento Tecnológico. Rio de Janeiro, RJ, Brasil. | pt_BR |
Subject | Brazil | pt_BR |
Subject | Epidemiology | pt_BR |
Subject | Hepatitis A | pt_BR |
Subject | Hepatitis A virus | pt_BR |
e-ISSN | 1365-2893 | |
Embargo date | 2022-01-01 | |