Author | Souza, Fernando Almeida | |
Author | Oliveira, Ana Elisa Reis de | |
Author | Silva, Ana Lucia Abreu | |
Author | Calabrese, Kátia da Silva | |
Access date | 2019-02-18T17:56:25Z | |
Available date | 2019-02-18T17:56:25Z | |
Document date | 2018 | |
Citation | SOUZA, Fernanda Almeida et al. In vitro activity of Morinda citrifolia Linn. fruit juice against the axenic amastigote form of Leishmania amazonensis and its hydrogen peroxide induction capacity in BALB/c peritoneal macrophages. BMC Research Notes, v. 11, n. 492, p. 1-7, 2018. | pt_BR |
ISSN | 1756-0500 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/31719 | |
Language | eng | pt_BR |
Publisher | BMC Research Notes | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | Leishmaniose | pt_BR |
Subject in Portuguese | Fitoterapia | pt_BR |
Subject in Portuguese | Atividade Antileishmanial | pt_BR |
Subject in Portuguese | Espécies reativas do oxigênio | pt_BR |
Subject in Portuguese | Morinda | pt_BR |
Subject in Portuguese | Peróxido de Hidrogênio | pt_BR |
Title | In vitro activity of Morinda citrifolia Linn. fruit juice against the axenic amastigote form of Leishmania amazonensis and its hydrogen peroxide induction capacity in BALB/c peritoneal macrophages | pt_BR |
Type | Article | pt_BR |
DOI | 10.1186/s13104‑018‑3555‑7 | |
Abstract | Objective: The current treatment of leishmaniasis induces strong side effects and increasing numbers of cases of resistance to reference drugs have been reported. The discovery of the therapeutic properties of active substances in plant extracts represents an interesting field of research into a more efficient treatment against leishmaniasis. Morinda citrifolia, commonly known as noni, has demonstrated promising results as antileishmanial and immunomodulator. Thus, the aim of this work was to evaluate activity against axenic amastigote and hydrogen peroxide induction capac‑ ity by M. citrifolia fruit juice. | pt_BR |
Affilliation | Universidade Estadual do Maranhão. São Luís, MA, Brasil / Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunomodulação e Protozoologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Universidade Estadual do Maranhão. São Luís, MA, Brasil. | pt_BR |
Affilliation | Universidade Estadual do Maranhão. São Luís, MA, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Imunomodulação e Protozoologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
Subject | Leishmaniasis | pt_BR |
Subject | MTT | pt_BR |
Subject | Phytotherapy | pt_BR |
Subject | H2O2 | pt_BR |
Subject | Reactive Oxygen Species | pt_BR |
Subject | Noni | pt_BR |
DeCS | Peróxido de Hidrogênio | pt_BR |