Please use this identifier to cite or link to this item:
https://www.arca.fiocruz.br/handle/icict/30263
PLANT-FEEDING PHLEBOTOMINE SAND FLIES, VECTORS OF LEISHMANIASIS, PREFER CANNABIS SATIVA
Leishmaniose
Sequenciamento de próxima geração
Flebotomíneos moscas de areia
Alimentação de plantas
Leishmaniasis
Next-generation sequencing
Phlebotomine sand flies
Plant feeding
Author
Abbasi, Ibrahim
Queiroz, Artur Trancoso Lopo de
Kirstein, Oscar David
Nasereddin, Abdelmajeed
Horwitz, Ben Zion
Hailu, Asrat
Salah, Ikram
Mota, Tiago Feitosa
Fraga, Deborah Bittencourt Mothé
Veras, Patrícia Sampaio Tavares
Poche, David
Poche, Richard
Yeszhanov, Aidyn
Brodskyn, Cláudia Ida
Poche, Zaria Torres
Warburg, Alon
Queiroz, Artur Trancoso Lopo de
Kirstein, Oscar David
Nasereddin, Abdelmajeed
Horwitz, Ben Zion
Hailu, Asrat
Salah, Ikram
Mota, Tiago Feitosa
Fraga, Deborah Bittencourt Mothé
Veras, Patrícia Sampaio Tavares
Poche, David
Poche, Richard
Yeszhanov, Aidyn
Brodskyn, Cláudia Ida
Poche, Zaria Torres
Warburg, Alon
Affilliation
The Hebrew University of Jerusalem. Faculty of Medicine Jerusalem. Institute for Medical Research Israel-Canada. The Kuvin Centre for the Study of Infectious and Tropical Diseases. Department of Microbiology and Molecular Genetics. Jerusalem, Israel.
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.
The Hebrew University of Jerusalem. Faculty of Medicine Jerusalem. Institute for Medical Research Israel-Canada. The Kuvin Centre for the Study of Infectious and Tropical Diseases. Department of Microbiology and Molecular Genetics. Jerusalem, Israel.
The Hebrew University of Jerusalem. Faculty of Medicine. Genomics Applications Laboratory. Core Research Facility. Jerusalem, Israel.
The Hebrew University of Jerusalem. Faculty of Medicine Jerusalem. Institute for Medical Research Israel-Canada. The Kuvin Centre for the Study of Infectious and Tropical Diseases. Department of Microbiology and Molecular Genetics. Jerusalem, Israel.
Addis Ababa University. School of Medicine. College of Health Sciences. Addis Ababa, Ethiopia.
Ben-Gurion University of the Negev. Blaustein Institutes for Desert Research. Mitrani Department of Desert Ecology. Midreshet Ben-Gurion, Israel.
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.
Genesis Laboratories, Inc. Wellington, CO, EUA.
Genesis Laboratories, Inc. Wellington, CO, EUA.
M. Aikimbayev Kazakh Scientific Center of Quarantine and Zoonotic Diseases. Almaty, Kazakhstan.
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.
Genesis Laboratories, Inc. Wellington, CO, EUA.
The Hebrew University of Jerusalem. Faculty of Medicine Jerusalem. Institute for Medical Research Israel-Canada. The Kuvin Centre for the Study of Infectious and Tropical Diseases. Department of Microbiology and Molecular Genetics. Jerusalem, Israel.
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.
The Hebrew University of Jerusalem. Faculty of Medicine Jerusalem. Institute for Medical Research Israel-Canada. The Kuvin Centre for the Study of Infectious and Tropical Diseases. Department of Microbiology and Molecular Genetics. Jerusalem, Israel.
The Hebrew University of Jerusalem. Faculty of Medicine. Genomics Applications Laboratory. Core Research Facility. Jerusalem, Israel.
The Hebrew University of Jerusalem. Faculty of Medicine Jerusalem. Institute for Medical Research Israel-Canada. The Kuvin Centre for the Study of Infectious and Tropical Diseases. Department of Microbiology and Molecular Genetics. Jerusalem, Israel.
Addis Ababa University. School of Medicine. College of Health Sciences. Addis Ababa, Ethiopia.
Ben-Gurion University of the Negev. Blaustein Institutes for Desert Research. Mitrani Department of Desert Ecology. Midreshet Ben-Gurion, Israel.
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.
Genesis Laboratories, Inc. Wellington, CO, EUA.
Genesis Laboratories, Inc. Wellington, CO, EUA.
M. Aikimbayev Kazakh Scientific Center of Quarantine and Zoonotic Diseases. Almaty, Kazakhstan.
Fundação Oswaldo Cruz. Instituto Gonçalo Moniz. Salvador, BA, Brasil.
Genesis Laboratories, Inc. Wellington, CO, EUA.
The Hebrew University of Jerusalem. Faculty of Medicine Jerusalem. Institute for Medical Research Israel-Canada. The Kuvin Centre for the Study of Infectious and Tropical Diseases. Department of Microbiology and Molecular Genetics. Jerusalem, Israel.
Abstract
Blood-sucking phlebotomine sand flies (Diptera: Psychodidae) transmit leishmaniasis as well as arboviral diseases and bartonellosis. Sand fly females become infected with Leishmania parasites and transmit them while imbibing vertebrates' blood, required as a source of protein for maturation of eggs. In addition, both females and males consume plant-derived sugar meals as a source of energy. Plant meals may comprise sugary solutions such as nectar or honeydew (secreted by plant-sucking homopteran insects), as well as phloem sap that sand flies obtain by piercing leaves and stems with their needle-like mouthparts. Hence, the structure of plant communities can influence the distribution and epidemiology of leishmaniasis. We designed a next-generation sequencing (NGS)-based assay for determining the source of sand fly plant meals, based upon the chloroplast DNA gene ribulose bisphosphate carboxylase large chain (rbcL). Here, we report on the predilection of several sand fly species, vectors of leishmaniasis in different parts of the world, for feeding on Cannabis sativa We infer this preference based on the substantial percentage of sand flies that had fed on C. sativa plants despite the apparent "absence" of these plants from most of the field sites. We discuss the conceivable implications of the affinity of sand flies for C. sativa on their vectorial capacity for Leishmania and the putative exploitation of their attraction to C. sativa for the control of sand fly-borne diseases.
Keywords in Portuguese
Cannabis sativaLeishmaniose
Sequenciamento de próxima geração
Flebotomíneos moscas de areia
Alimentação de plantas
Keywords
Cannabis sativaLeishmaniasis
Next-generation sequencing
Phlebotomine sand flies
Plant feeding
Share