Author | Santos, Debora Regina Lopes dos | |
Author | Paula, Vanessa Salete de | |
Author | Oliveira, Jaqueline Mendes de | |
Author | Marchevsky, Renato Sérgio | |
Author | Pinto, Marcelo Alves | |
Access date | 2018-11-18T16:05:01Z | |
Available date | 2018-11-18T16:05:01Z | |
Document date | 2011 | |
Citation | SANTOS, Debora Regina Lopes dos; et al. Hepatitis E virus in swine and effluent samples from slaughterhouses in Brazil. Veterinary Microbiology, v.149, n.1-2, p.236-241, April 2011. | pt_BR |
ISSN | 0378-1135 | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/30074 | |
Language | eng | pt_BR |
Publisher | Elsevier | pt_BR |
Rights | open access | pt_BR |
Subject in Portuguese | segurança alimentar | pt_BR |
Subject in Portuguese | suínos | pt_BR |
Subject in Portuguese | Hepatite E | pt_BR |
Subject in Portuguese | Zoonose | pt_BR |
Subject in Portuguese | Brasil | pt_BR |
Title | Hepatitis E virus in swine and effluent samples from slaughterhouses in Brazil | pt_BR |
Type | Article | pt_BR |
DOI | 10.1016/j.vetmic.2010.10.024 | |
Abstract | Hepatitis E is an infectious disease which virus (HEV) is highly disseminated in swine herd populations. Sporadic acute human hepatitis E cases have been associated to genotype 3 and 4 strains of HEV also reported in swine populations of endemic and non-endemic areas. With the aim to evaluate the incidence of animals with current infection of HEV, 115 bile samples were collected from three slaughterhouses under inspection by Animal Sanitary Protection Agency of Rio de Janeiro, Brazil. In parallel, effluent samples were collected from six sewage pipe exit sites of two slaughterhouses. HEV RNA was detected in 11 out of 115 (9.6%) bile samples collected and three waste samples from one slaughterhouse. Viral loads observed for bile samples varied from 10(1)-10(5) genome copies/mL and for effluent samples mean load was 10(2) genome copies/mL. Sequencing and phylogenetic analysis classified samples within genotype 3 subtype 3b closely related to the sample obtained from the first reported autochthonous human case and samples from swine of commercial herds in Brazil. Our data demonstrates that although most animals achieve slaughter age (around 20 weeks old) already immune to HEV, a significant number of animals are with current infection at commercial age. Further studies should be addressed to consider risk analysis and possible evaluation of inspection regulations considering food safety measures regarding hepatitis E zoonotic aspect in Brazil. | pt_BR |
Affilliation | Universidade Federal Rural do Rio de Janeiro. Instituto de Veterinária. Departamento de Microbiologia e Imunologia Veterinária. Laboratório de Imunologia e Virologia Veterinária. Seropédica, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Desenvolvimento Tecnológico em Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Desenvolvimento Tecnológico em Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Bio-Manguinhos. Laboratório de Neuro-Virulência. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Oswaldo Cruz. Laboratório de Desenvolvimento Tecnológico em Virologia. Rio de Janeiro, RJ, Brasil. | pt_BR |
Subject | Swine | pt_BR |
Subject | Hepatitis E | pt_BR |
Subject | Zoonosis | pt_BR |
Subject | Food safety | pt_BR |
Subject | Brazil | pt_BR |