Author | Gandhi, Monica | |
Author | Glidden, David V. | |
Author | Mayer, Kenneth | |
Author | Schechter, Mauro | |
Author | Buchbinder, Susan | |
Author | Grinsztejn, Beatriz | |
Author | Hosek, Sybil | |
Author | Casapia, Martin | |
Author | Guanira, Juan | |
Author | Bekker, Linda-Gail | |
Author | Louie, Alexander | |
Author | Horng, Howard | |
Author | Benet, Leslie Z. | |
Author | Liu, Albert | |
Author | Grant, Robert M. | |
Access date | 2018-10-03T16:03:48Z | |
Available date | 2018-10-03T16:03:48Z | |
Document date | 2016 | |
Citation | GANDHI, Monica. et al. Age, Baseline Kidney Function, and Medication Exposure Are Associated with Declines in Creatinine Clearance on PrEP: An Observational Cohort Study. The lancet HIV, v. 3, n. 11, p. e521–e528, 2016. | pt_BR |
URI | https://www.arca.fiocruz.br/handle/icict/29286 | |
Language | eng | pt_BR |
Rights | open access | pt_BR |
Title | Association of age, baseline kidney function, and medication exposure with declines in creatinine clearance on pre-exposure prophylaxis: an observational cohort study | pt_BR |
Type | Article | pt_BR |
DOI | 10.1016/S2352-3018(16)30153-9 | |
Abstract | As pre-exposure prophylaxis (PrEP) with tenofovir disoproxil fumarate and emtricitabine for the prevention of HIV infection is rolled out internationally, strategies to maintain effectiveness and to minimise adverse effects merit consideration. In this study, we aimed to assess reductions in renal function and predictors of renal toxicity in a large open-label study of PrEP. | |
Affilliation | Division of HIV, Infectious Diseases, and Global Medicine. University of California, San Francisco. San Francisco, CA, USA. | pt_BR |
Affilliation | Department of Biostatistics and Epidemiology. University of California San Francisco. San Francisco, CA, USA | pt_BR |
Affilliation | Fenway Health. Boston, MA, USA. | pt_BR |
Affilliation | Universidade Federal do Rio de Janeiro. Hospital Escola São Francisco de Assis. Projeto Praça Onze. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | San Francisco Department of Public Health. San Francisco, CA, USA. | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Instituto Nacional de Infectologia Evandro Chagas. Laboratório de Pesquisa Clínica em DST/AIDS. Rio de Janeiro, RJ, Brasil. | pt_BR |
Affilliation | Department of Psychiatry. Stroger Hospital of Cook County. Chicago, IL, USA. | pt_BR |
Affilliation | Asociacion Civil Selva Amazonica (ACSA) CRS. Iquitos, Peru. | pt_BR |
Affilliation | Investigaciones Médicas en Salud. Lima, Peru. | pt_BR |
Affilliation | Desmond Tutu Health Foundation. Faculty of Health Sciences. Cape Town, South Africa. | pt_BR |
Affilliation | Department of Medicine. University of California, San Francisco. San Francisco, CA, USA. | pt_BR |
Affilliation | Department of Bioengineering and Therapeutic Sciences. University of California, San Francisco. San Francisco, CA, USA. | pt_BR |
Affilliation | HIV Prevention Intervention Studies Bridge HIV. San Francisco, CA, USA. | pt_BR |
Affilliation | Division of Pulmonary and Critical Care Medicine. University of California, San Francisco. San Francisco, CA, USA. | pt_BR |
Subject | HIV prevention | pt_BR |
Subject | Pre-exposure prophylaxis (PrEP) | pt_BR |
Subject | Pharmacologic measures | pt_BR |
Subject | Tenofovir/emtricitabine | pt_BR |
Subject | Hair concentrations | pt_BR |
Subject | iPrEx Open Label Extension (OLE) | pt_BR |
Subject | Renal decline | pt_BR |
Subject | Creatinine clearance | pt_BR |
Embargo date | 2018-12-03 | |