Author | Lins, Liliane | |
Author | Almeida, Herbert | |
Author | Vitvitski, Ludmila | |
Author | Carmo, Theomira Mauadie de Azevedo | |
Author | Paraná, Raymundo | |
Author | Reis, Mitermayer Galvão dos | |
Access date | 2011-07-28T18:27:28Z | |
Available date | 2011-07-28T18:27:28Z | |
Document date | 2005 | |
Citation | LINS, L. et al. Detection of hepatitis C virus RNA in saliva is not related to oral health status or viral load. Journal of Medical Virology, v. 77, n. 2, p. 216-220, 2005. | pt_BR |
ISSN | 0146-6615 | |
URI | https://www.arca.fiocruz.br/handle/icict/2785 | |
Language | eng | pt_BR |
Rights | open access | |
Subject in Portuguese | Hepacivirus | pt_BR |
Subject in Portuguese | RNA Viral | pt_BR |
Subject in Portuguese | Saliva | pt_BR |
Subject in Portuguese | Anticorpos Anti-Hepatite | pt_BR |
Subject in Portuguese | Genes Virais | pt_BR |
Subject in Portuguese | Carga Viral | pt_BR |
Title | Detection of Hepatitis C Virus RNA in Saliva Is Not Related to Oral Health Status or Viral Load | pt_BR |
Type | Article | pt_BR |
DOI | 10.1002/jmv.20438 | |
Abstract | Hepatitis C is a worldwide public health problem and its transmission is clearly associated with the parenteral route, however, the virus has also been isolated from other body fluids. Hepatitis C virus (HCV) RNA has been detected in saliva, yet the relationship between HCV and oral pathology is not clearly understood. Therefore, an investigation on HCV-RNA in saliva and its correlation with oral pathology was undertaken. Saliva and blood samples were collected from 50 anti-HCV positive patients and from 25 patients with non-HCV chronic liver disease. HCV-RNA was detected in all of the saliva samples from the HCV positive group. None of the saliva or serum samples from the non-HCV group were positive for HCV-RNA. The patients were examined for dental and oral health (dentate, partially dentate, edentulous, evidence of gum disease, or mucosal lesions); however, no correlation was found between HCV-RNA in saliva, oral health, and viral load. These results suggest that HCV-RNA presence in saliva is independent of the viral load and the oral pathology of HCV positive individuals | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | Universidade Federal da Bahia. Faculdade de Medicina. Salvador, BA, Brazil | pt_BR |
Affilliation | INSERM U271. Lyon, France | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
Affilliation | Universidade Federal da Bahia. Faculdade de Medicina. Salvador, BA, Brazil | pt_BR |
Affilliation | Fundação Oswaldo Cruz. Centro de Pesquisas Gonçalo Moniz. Salvador, BA, Brasil | pt_BR |
DeCS | Hepacivirus | pt_BR |
DeCS | RNA Viral | pt_BR |
DeCS | Saliva | pt_BR |
DeCS | Anticorpos Anti-Hepatite | pt_BR |